Tag: Genetics
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Using Genomics to Understand the Severity of Bacterial Infections
Northwestern Medicine investigators have uncovered a novel pathogenic mechanism used by the bacterium Pseudomonas aeruginosa to promote more severe infections.
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Centrioles Aid Cellular Migration
A new study has found cells with high numbers of centrioles more quickly migrated through layers of tissue, a process known as radial intercalation, which may provide new insights into the development of many cancers.
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New Insights into Chromosome Folding
A new study has helped solve the mystery of how dysfunctional chromosome folding leads to cancer.
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Elevated Gene Expression Linked to Poor Glioblastoma Survival
The elevated expression of a gene called LY6K was correlated with increased cancer cell growth and resistance to radiation therapy in glioblastoma, according to a recent Northwestern Medicine study.
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Rewriting the Role of a Transcription Factor
A DNA transcription mechanism does not work as previously thought, according to a new Northwestern Medicine study.
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Genetic Toolkit Supports Development of Customized Cancer Therapies
A novel genetic toolkit developed by Northwestern Medicine scientists may support the development of customized therapeutic interventions for a breadth of diseases, according to a recent study published in Nature Communications.
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Gene Pathway Shows Therapeutic Potential for Treatment of Autoimmune Diseases
A team of Northwestern Medicine investigators identified a specific gene as a key regulator of immune cells called invariant natural killer T cells, which may present therapeutic potential for the treatment of autoimmune diseases.
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Unwrapping Oligodendrocyte Development
The development of oligodendrocytes are heavily influenced by an RNA epigenetic regulation mechanism, according to a new study.
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Chromatin Organizes Itself Into 3D ‘Forests’ in Single Cells
Using mathematical modeling and optical imaging they developed themselves, a Northwestern University research team has discovered how chromatin folds at the single-cell level.
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‘Soft’ Symptoms Detected Before Parkinson’s Disease
People who carry genetic mutations associated with an increased risk for Parkinson’s disease may exhibit minor symptoms long before the disease progresses to affect daily life, according to a study of over 300 patients.
