Category: Clinical Breakthroughs
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Combination Treatment May Slow Disease Progression in Advanced Sarcoma
An oral combination treatment may prevent disease progression in patients with advanced leiomyosarcoma, one of the most common subtypes of soft tissue sarcoma, according to a recent study published in The Lancet Oncology.
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Study Finds Widespread Screening for Rare Cholesterol Disorder Not Cost-Effective
Screening all young people for a genetic form of dangerously high cholesterol could prevent heart attacks and strokes later in life, but would not be cost-effective under the current healthcare system, according to a new modelling study published in JAMA.
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First-Of-Its-Kind Probe Monitors Fetal Health in Utero During Surgery
Northwestern University researchers have developed the first device that can continuously track a fetus’s vital signs while still in the uterus — a feat that previously has not been possible.
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Identifying Mechanisms Supporting Nanoparticle Therapy for Autoimmune Diseases
Northwestern Medicine scientists in the laboratory of Stephen Miller, PhD, have identified the cellular and molecular mechanisms required for the antigen-specific tolerance inducing abilities of a novel nanoparticle therapy for treating autoimmune diseases, according to a recent study published in Science Advances.
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Common Procedure Does Not Prevent Recurrent Pancreatitis, Trial Finds
A multicenter clinical trial published in JAMA has found that a long-used endoscopic procedure does not prevent recurrent pancreatitis in adults with an anatomic anomaly, challenging decades of conventional wisdom.
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Non-invasive Approach Predicts Chemotherapy Response in Glioblastoma
Northwestern Medicine scientists have developed a new non-invasive approach that could help better determine which patients with glioblastoma are responding favorably to chemotherapy treatment and inform future treatment plans, according to a recent study published in Nature Communications.
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Evaluating Treatment of Heart Defects in Preterm Infants
Early pharmacologic treatment of a common congenital heart defect did not improve survival outcomes compared to expectant management in preterm infants, according to a recent clinical trial published in JAMA.
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Investigating Treatments for Peripheral Artery Disease
A common diabetes medication does not help people with peripheral artery disease (PAD) walk farther, according to results from a major U.S. clinical trial published in JAMA.
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Experimental Drug Shows Promise for Rare Genetic Disorder
A new experimental therapy has shown encouraging results in treating a rare and progressive lysosomal storage disorder, according to findings from a multi-year clinical trial published in the New England Journal of Medicine.
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Gestational Diabetes Rose Every Year in the US Since 2016
Gestational diabetes rose every single year in the U.S. from 2016 through 2024, according to a new Northwestern Medicine analysis of more than 12 million U.S. births.
