Inter-Organelle Contact Drives Calcium Transfer
Inter-organelle contacts drive calcium transfer from lysosomes to mitochondria, findings that lay out a possible therapeutic blueprint for neurological disorders.
Browsing: Scientific Advances
Scientists Develop New Method to Trace Cell Lineage
Northwestern Medicine scientists have developed a novel cell lineage tracing method that can better determine the origin of mammalian neuron populations from progenitor cells.
Mitochondrial Metabolism Shows Promise as Target for Cancer Therapy
Northwestern Medicine investigators have discovered that the growth of cancerous tumors requires the activation of a specific biochemical process within the mitochondria of tumor cells, showing potential as a new target for cancer therapy.
Protein Unexpectedly Impacts Intracellular Transport in Neurons
Northwestern Medicine investigators have discovered that a specific protein known for its role in cell division also impacts the direction of intracellular transport in neurons.
Critical Function of Cilia Protein Discovered
A protein gives motile cilia part of their structure, according to a recent Northwestern Medicine study.
New Role for RNA Splicing in Insulin Regulation
The gene transcription machinery that controls circadian rhythms also regulates insulin release in the pancreas, according to a Northwestern Medicine study.
Exploring Protein Vital for Bone Marrow Transplants
A protein called mDia2 is vital for proper bone marrow transplantation, according to a new study.
New Genetic Regulators Could Improve Cancer Immunotherapy
A genetic screen has revealed previously unknown regulators of Foxp3, a transcription factor that, when deactivated, may improve patient response to aggressive cancers.
Brain Synchronization Improves Odor Perception
Neurons in the olfactory cortex coordinate to boost the sense of smell when anticipating an odor, according to a Northwestern Medicine study.
Feet on the Ground
Building equitable relationships with community leaders and framing research questions around residents’ priorities is the core principle of community-engaged research, and IPHAM, along with ARCC, have been leaders in the field.