A team of scientists has identified a key enhancer of Sox9 — a gene critical for male sex development — and demonstrated that deleting the enhancer results in male-to-female sex reversal in animal models.
Enhancing autophagy, the system that recycles old or dysfunctional cells, could have therapeutic effects in a variety of aging-related diseases, according to a pair of Northwestern Medicine studies.
A Northwestern Medicine study has expanded the understanding of nicotine’s influences on the brain’s reward pathway, with implications for the development of anti-addiction therapies.
A study, published in Proceedings of the National Academy of Sciences, provides new insights into the organization of a key protein called cadherin within structures called adherens junctions, which help cells stick together.
New study demonstrates the midbrain’s role in encoding identity errors and how those are used to update expectations in the orbitofrontal cortex.
Scientists found more than 100 possible cancer-causing mutations and defective alleles in a large-scale genetic analysis of pediatric cancers that was co-authored by Elizabeth Perlman, MD, and published in Nature.
The newly-launched Center for Autism and Neurodevelopment is a translational science hub that aims to investigate the neurobiology of autism and facilitate the development of new treatments.
A team of scientists has developed a new technique that allows investigators to better study the effects of nicotine on brain cells.
Northwestern Medicine scientists have uncovered how DNA methylation triggers stem cells to transform into more specialized neuronal cells.
Northwestern Medicine scientists have identified a signaling protein that regulates cell organization, with implications for early development and certain diseases.