Genome Editing Made Possible on Cells Lining Blood Vessel Walls
The laboratory of YouYang Zhao, PhD, developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to vascular endothelial cells.
Browsing: Scientific Advances
Secondary Structures in DNA are Associated With Cancer
A new Northwestern Medicine study reports that DNA manifested as knot-like folds and third rungs between DNA’s two strands may drive cancer development and an important regulatory enzyme could be associated with the formation of these unusual structures.
Study Finds Marijuana Use Increasing Among Pregnant Individuals with HIV
Marijuana use among pregnant and postpartum individuals living with HIV increased from 2007 to 2019, according to a Northwestern Medicine study.
Protein ‘Chaperone’ Plays Dual Role in DNA Replication
The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.
Histone Protein Influences Both Neurological Disorder and Cancer
Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
County-Level Poverty Associated with Risk of Gun Death in Children
Living in U.S. counties with higher concentrations of poverty was associated with increased risk of firearm-related deaths among children and young adults, according to a recent study.
Uncovering the Degenerative Basis of Parkinson’s Disease
Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons that increases their vulnerability to degeneration.
Mistreatment is Common Among LGBTQ Surgery Residents
U.S. surgical residents who identify as LGBTQ+ reported higher rates of mistreatment in their training programs than their non-LGBTQ+ peers, according to a Northwestern Medicine study.
Neurobiologists Identify a New Gene Important for Healthy Daily Rhythms
A recent study identified a gene that is critical for daily behavioral rhythms, involved in a molecular pathway by which the core circadian clock controls daily sleep-wake cycles.
New Insights into Cell Polarity
A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.