Protein Protects Nucleus from Rupture
A cytoskeletal protein called vimentin helps prevent the nuclei of cells that must navigate through tight spaces in the body from rupturing, according to a recent study.
Browsing: Scientific Advances
African Ancestry Affects Gene Expression
Levels of African ancestry in a person’s genome determines the level at which certain genes are expressed, findings that could offer insight into the different risk of diseases.
Lymphatic Capillaries Help Regulate Stem Cells for Tissue Regeneration
Lymphatic capillaries help regulate the niche microenvironment surrounding stem cells, which promote the regeneration of hair follicles after injury or damage, according to a study published in Science.
Study Finds Many Visiting Healthcare Professionals Perform Outside their Training Overseas
A Northwestern Medicine study found that almost 30 percent of healthcare professionals and trainees from high-income countries have performed outside their scope of training while working or volunteering in low- and middle-income countries.
Hidden Data in ‘Junk DNA’ May Predict Cancer
A new machine-learning tool demonstrates the clinical potential of ‘junk DNA’ methylation in hepatitis C-associated liver cancer patients without the need for expensive testing.
Tissue Environment Shapes Gene Regulation in Skeletal Muscles
The tissue environment and chronic exercise can both influence gene expression in skeletal muscles, according to a study published in PLOS Biology.
Northwestern Scientists Develop New Probes to Investigate the Brain
Northwestern scientists have developed a battery-free, wireless device for studying brain function using a combination of light and drugs, publishing their design in PNAS.
New Link Between Mitochondria and Neurodegeneration
A study published in the Journal of Cell Biology showed that mitochondrial stress in neurons can cause an enzyme imbalance that contributes to neuronal dysfunction and death.
Overexpression of Enzyme Increases Risk of Treatment Failure in Breast Cancer
The overexpression of mitochondrial superoxide dismutase, commonly found in late-stage tumors, may drive cancer stem cell formation and contribute to the failure of chemotherapy treatment in breast cancer patients.
Experimental Drug May Reduce Cancer Growth and Progression
Scientists co-led by Sui Huang, MD, PhD, found an experimental drug called metarrestin significantly reduced metastasis and cancer progression in mouse models.