
Northwestern Medicine scientists have developed a novel high-resolution 3D spatial genomics platform that may enhance future research about how genome organization and genetic alterations contribute to the development of disease, including cancer, as detailed in a recent study published in Nature Methods.

Loneliness can reprogram the brain in ways that push alcohol consumption, reports a new preclinical study led by Northwestern University and the Salk Institute for Biological Studies.

A new Northwestern Medicine study has uncovered key molecular design principles that could help supramolecular therapeutics cross the blood-brain barrier, a major challenge for the novel approach to treating neurological disorders.


Northwestern scientists have developed a DNA-driven process to induce protein crystallization that can help reveal protein structures and enable the development of new flexible biomaterials.

New Northwestern Medicine research published in Nature Communications suggests that a metabolite produced by gut bacteria when they digest dietary fiber can leave a lasting molecular imprint on intestinal cells, promoting immune tolerance and protecting against inflammatory bowel disease-like conditions long after exposure ends.

A new Northwestern Medicine study has uncovered how a key immunoregulatory receptor plays an unexpected dual role in promoting T-cell exhaustion during chronic infection and cancer, according to findings published in the Proceedings of the National Academy of Sciences.

A new Northwestern Medicine study has introduced a novel machine learning method for understanding how the brain organizes complex behaviors, offering fresh evidence that neural activity is built from reusable “building blocks,” according to the study published in Neuron.

A new Northwestern Medicine study published in the Proceedings of the National Academy of Sciences has explored the impacts of aging on essential cellular processes, findings that could shape the development of future anti-aging therapeutic strategies.

Northwestern Medicine scientists have discovered that one of the body’s most fundamental biological processes — how red blood cells are made — works differently in humans than previously thought, according to a new study published in Nature Genetics.