Northwestern Medicine scientists have recently discovered that two common genetic risk factors for Parkinson’s disease can be regulated with LRRK2 kinase inhibition or GCase enzyme activation, revealing potential for the development of new therapeutics.
People who carry genetic mutations associated with an increased risk for Parkinson’s disease may exhibit minor symptoms long before the disease progresses to affect daily life, according to a study of over 300 patients.
Scientists have discovered a set of neural “conversations” underlying individual neurons’ activity during learned movements, findings with implications for the development of neuroprostheses.
A Northwestern Medicine study found that episodic memory may be improved through the use of noninvasive transcranial magnetic stimulation of the posterior medial network in the hippocampus.
Listen to a selection of the most popular episodes of the Breakthroughs podcast series produced in 2019, including a possible Amish fountain of youth, artificial intelligence, the rise of food allergies and more.
A new lipid nanoparticle drug helped make tumor cells more vulnerable to therapy, significantly prolonging survival in models of glioblastoma.
Scientists have discovered why a specific genetic mutation causes intellectual disability and autism spectrum disorder in children.
A one-of-a-kind drug created to treat a single patient passed a crucial test at Northwestern, according to a study published in the New England Journal of Medicine.
Northwestern scientists have developed a battery-free, wireless device for studying brain function using a combination of light and drugs, publishing their design in PNAS.
A study published in the Journal of Cell Biology showed that mitochondrial stress in neurons can cause an enzyme imbalance that contributes to neuronal dysfunction and death.