Tag: Cancer
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Combination Treatment May Slow Disease Progression in Advanced Sarcoma
An oral combination treatment may prevent disease progression in patients with advanced leiomyosarcoma, one of the most common subtypes of soft tissue sarcoma, according to a recent study published in The Lancet Oncology.
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AI Model May Improve RNA Sequencing Research
Scientists in the laboratory of Rendong Yang, PhD, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more accurately than conventional approaches, as detailed in a recent study published in Nature Communications.
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Non-invasive Approach Predicts Chemotherapy Response in Glioblastoma
Northwestern Medicine scientists have developed a new non-invasive approach that could help better determine which patients with glioblastoma are responding favorably to chemotherapy treatment and inform future treatment plans, according to a recent study published in Nature Communications.
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New Underlying Mechanisms May Support Proper Transcriptional Regulation and Improve Targeted Therapies
Northwestern Medicine scientists have discovered new mechanisms underlying transcriptional initiation and elongation control that support proper gene expression, which may inform targeted therapeutic approaches for many diseases, according to a recent study published in Molecular Cell.
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How Inflammation Fuels Blood Cancer Risk
A Northwestern Medicine-led study published in The Journal of Clinical Investigation has uncovered why older individuals with specific genetic mutations face a heightened risk of developing serious blood cancers.
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Investigating HIV’s Hidden Immune Evasion Strategy
A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding detection.
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Tanning Beds Triple Melanoma Risk, Potentially Causing Broad DNA Damage
Tanning bed use is tied to almost a threefold increase in melanoma risk, and for the first time, scientists have shown how these devices cause melanoma-linked DNA damage across nearly the entire skin surface, according to a recent study.
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Scientists Map the Human Genome in 4D
In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome’s three‑dimensional organization across time and space, according to a new study published in Nature.
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Noninvasive Treatment Boosts Immune Response Against Glioblastoma
Northwestern Medicine scientists, along with collaborators from the Washington University School of Medicine, have developed a noninvasive nanomedicine approach that may improve the treatment of glioblastoma, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Novel Biomarker May Predict Immunotherapy Resistance
Northwestern Medicine scientists have identified a novel biomarker for immune immunotherapy resistance in cancer that may also serve as a potential therapeutic target for patients who don’t respond well to immunotherapy, according to a recent study published in The Journal of Clinical Investigation.
