Tag: Cancer
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Understanding Treatment Response in High-Risk Bladder Cancer
A new study may pave the way toward more personalized treatments for patients with high-risk bladder cancer, according to a study published in European Urology.
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Scans Can Reveal Hidden Prostate Cancer Progression
A large analysis of two major clinical trials has found that the spread of prostate cancer can be detected on imaging scans even when biomarkers remain stable, according to a study published in the Journal of Clinical Oncology.
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Understanding Cancer’s Hidden Vulnerabilities
Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new layer of genetic regulation that could reshape how certain cancers are treated.
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New Drug Doubles One-Year Survival in Pancreatic Cancer Trial
Patients who received an experimental drug developed at Northwestern University alongside standard chemotherapy were twice as likely to be alive after one year of treatment, compared to those receiving chemotherapy alone.
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Targeting Novel Long Non-Coding RNA May Improve Glioblastoma Treatment
Scientists have discovered that increased expression of a novel long non-coding RNA drives glioblastoma cell growth alongside a genetic amplification found in more than half of glioblastoma tumors, according to a Northwestern Medicine study published in Nature Cell Biology.
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Long Non-Coding RNA May be a Promising Therapeutic Target for Cancer
Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its potential as a therapeutic target, according to a recent study published in Nature Communications.
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Overlooked Cells Linked to Poor Outcomes in Breast Cancer
A little-studied group of cancer cells circulating in the bloodstream may play a bigger role in breast cancer progression than previously thought, according to new research published in Science Translational Medicine that sheds light on how the disease spreads and why some patients fare worse than others.
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Transcription Factors Form Continuous ‘Circuit’ That Regulates T-cell Exhaustion
Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic strategies for managing infections and cancer, according to a recent Northwestern Medicine study.
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Fructose Uptake in Immune Cells Promotes Glioblastoma Growth
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor microenvironment metabolize fructose to suppress immune responses and promote tumor growth, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Calcium Signaling Channels Regulate Neuroinflammation and Motivation
Northwestern Medicine scientists have discovered how calcium signaling channels in the brain’s immune cells regulate neuroinflammation and promote the development of behaviors associated with affective mood disorders, according to a recent study published in Science Signaling.
