Inhibiting SAM Biosynthesis to Slow Tumor Growth
Inhibiting production of a key material produced by the mTOR pathway could slow tumor growth, according to a recent Northwestern Medicine study.
Browsing: "Cancer"
Protein Variant May Have Potential as Target for Glioblastoma
Inhibiting a novel protein variant within glioma stem cells may be a promising therapeutic approach to treat glioblastoma, according to a recent Northwestern Medicine study.
Bioinformatic Computational Tool Analyzes Tissue Samples to Discern Disease
A novel integrative computational technique allowed scientists to classify disease conditions at the molecular level using epigenomic data sets.
Northwestern Scientists Discover Potential Therapeutic Target for Glioblastoma
Northwestern Medicine investigators have discovered that inhibiting tumor-associated myeloid cells ability to produce specialized metabolites called polyamines may improve the effectiveness of treatments for glioblastoma.
Antibody Bolsters Immune Response to Glioblastoma
Northwestern Medicine scientists have engineered a novel antibody that revitalizes immune cell activity in a deadly brain cancer, according to a recent study.
New Spherical Nucleic Acid ‘Drug’ Kills Tumor Cells in Humans With Glioblastoma
An experimental spherical nucleic acid drug developed by Northwestern scientists was able to penetrate the blood-brain barrier and trigger the death of glioblastoma cells.
Evaluating Perioperative Chemotherapy for Pancreatic Cancer
Perioperative chemotherapy treatment did not improve overall survival for patients with resectable pancreatic cancer, according to a recent Northwestern Medicine clinical trial.
Blocking Cell Division in Glioblastoma
Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
Identifying Therapeutic Targets for B-cell Acute Lymphoblastic Leukemia
Northwestern Medicine investigators have identified a protein kinase called DYRK1A and its downstream substrates as potential therapeutic targets for treating pediatric patients with B-cell acute lymphoblastic leukemia.
Antibody Drug Improves Survival for Aggressive Breast Cancer
A new antibody drug demonstrated similar efficacy to currently available therapies to treat advanced ERBB2-positive breast cancer, according to a recent clinical trial.