An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.
Northwestern’s Brain Tumor SPORE — part of the Lurie Cancer Center — is now three years old, and the bench to bedside process is producing results.
Blocking an inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.
Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a Northwestern Medicine study.
Harmful side effects from a common chemotherapy drug could be prevented in patients with a specific mutation by targeting retinoic acid receptors, according to a recent study.
Circulating tumor cells use the surface protein ICAM1 to strengthen stem cell programs and facilitate formation of tumor cell clusters, which can travel from primary tumors to other organs in the body.
Northwestern Medicine physician-scientist Amy Heimberger, MD, has been named by President Biden to the National Cancer Advisory Board, which plays an important role in setting the course for the nation’s cancer research programs.
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has been awarded a five-year, $9.2 million grant renewal from the National Cancer Institute to continue a Specialized Program of Research Excellence (SPORE) in prostate cancer.
A colonoscopy maneuver to better detect polyps in the right colon is often poorly preformed in practice, according to a Northwestern Medicine study.
Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of two oncogenes in glioma cells, which may improve personalized approaches to treat these cancers.