Category: Disease Discoveries
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Understanding the Link Between Genetic Risk and Brain Communication Disorders
A new Northwestern Medicine study suggests a major psychiatric risk gene remains important well into adulthood and may influence brain communication, according to a study published in the Proceedings of the National Academy of Sciences.
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Investigating Tumor Growth After Immunotherapy
A new Northwestern Medicine study has uncovered a biological mechanism that may explain why a subset of tumors unexpectedly grows at an accelerated rate after being treated with certain immunotherapies, according to findings published in Cancer Discovery.
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Experimental Drug May Disrupt Immune Circuits in Pneumonia
A drug that blocks calcium release-activated calcium channels may help interrupt harmful immune cell interactions that drive severe viral pneumonia, according to a new study published in The Journal of Clinical Investigation.
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Targeting Protein Synthesis Control Regions May Reduce Seizures in Genetic Epilepsy
Targeting the control of protein synthesis in the KCNQ2 gene may serve as a potential disease-modifying strategy for patients with a genetic form of neonatal-onset epilepsy and impaired brain development, according to a Northwestern Medicine study published in Proceedings of the National Academy of Sciences.
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Extreme Heat Linked to 33 Diagnoses That Go Beyond Dehydration, Heat Stroke
A new Northwestern University study suggests that extreme heat is linked to a much wider range of health problems seen in emergency departments and urgent care clinics than previously expected.
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Enzyme Utilizes Specialized Mechanisms to Promote Cancer Cell Proliferation
A new Northwestern Medicine study has identified a previously unknown mechanism by which the NAT10 enzyme promotes cancer cell proliferation, establishing this protein as a promising therapeutic target for cancer.
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Novel Stem Cell Platform Improves Study of Endometriosis
Scientists led by Julie Kim, PhD, have developed a novel stem cell platform that provides a new way to study the biology of endometriosis in humans more accurately than current model systems, as detailed in a recent study published in Science Advances.
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New Cellular Clues to Complications of Scleroderma
A recent Northwestern Medicine study published in JCI Insight has uncovered new clues about why people with systemic sclerosis, also known as scleroderma, frequently develop debilitating esophageal complications.
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Oxidative Stress Drives Rare Disease Flare-ups, Study Finds
Northwestern Medicine scientists have uncovered a mechanism that may explain why people with Darier disease, a rare genetic skin disorder, often develop symptoms years after birth and experience painful flare-ups triggered by heat, sunlight and psychological stress.
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Tumor-Like Tissue Environments Could Hold Clues to Curing HIV
The tissue microenvironments surrounding HIV-infected immune cells look a lot like those surrounding cancerous tumors, according to a new Northwestern study.
