Cilia Defects Linked to Schizophrenia
Mutations in PCM1, a gene involved in the formation of cilia, were linked with schizophrenia in a variety of animal models and in human genome analysis, according to a recent study.
Browsing: Disease Discoveries
Uncovering the Impact of Protein Mutations in Parkinson’s
Northwestern scientists have determined how two protein mutations responsible for the impaired motor function in Parkinson’s disease independently disrupt neuron activity.
New Path Forward for Pancreatic Cancer Treatment
Combining the current standard-of-care chemotherapy drug with a genetic inhibitor may improve treatment for pancreatic ductal adenocarcinoma, according to a recent study published in PNAS.
Investigating the Biology of Aging
Feinberg investigators are breaking down the mechanisms of aging and designing solutions to extend healthy living.
McNally Discusses COVID-19 Antibody Study Results, Next Steps
During a recent webinar, Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, discussed findings from the ongoing Screening for Coronavirus Antibodies in Neighborhoods (SCAN) study and what genetics can reveal about COVID-19.
Viral Protein Rewires B-Cells to Promote Infection
A viral protein of the Epstein-Barr virus previously thought to mimic immune cell receptor signaling actually rewires intracellular signaling in infected cells, promoting viral cell survival and proliferation.
Astrocytes Play Unexpected Role in Parkinson’s Disease
Astrocytes may play a protective role in Parkinson’s disease, slowing alpha-synuclein accumulation in neurons, according to a study published in The Journal of Neuroscience.
Feinberg Investigator Receives $1.8 million CDC Grant for Gun Violence Prevention Research
The three-year grant from the Centers for Disease Control and Prevention will fund the first-ever study looking at how sibling relationships influence firearm involvement.
New Brain Tumor Imaging Detects Smaller Tumors Sooner
A new three-dimensional imaging technique invented by Northwestern scientists greatly improves the visibility of brain tumors in magnetic resonance imaging scans.
Targeting Proteins May Help Eliminate Radioresistant Breast Cancer Cells
Targeting the proteins CD47 and HER2 may eliminate radioresistant breast cancer cells and enable more effective radiotherapy treatments for patients, according to a new study.