Critical Mass
Armed with a prestigious new grant, investigators prepare to rapidly translate scientific breakthroughs into better brain tumor therapies. Read the story in Northwestern Medicine magazine.
Browsing: Disease Discoveries
New Inhibitor Improves Autism-Like Symptoms in Mice
A Northwestern University experimental therapeutic targeting a specific protein kinase reversed neurological symptoms in a mouse genetic model of autism, according to a recent Northwestern Medicine study.
New Therapeutic Target for Metabolic Disorders
Scientists have identified a novel regulator of liver metabolism, which could serve as a potential therapeutic target for obesity, type 2 diabetes and related conditions.
Mechanisms of Mitochondrial Dysfunction in ALS
Northwestern Medicine scientists have demonstrated that mitochondrial damage plays a critical early role in a group of diseases, including forms of ALS and dementia.
Inflammation Can Lead to Circadian Sleep Disorders
Inflammation has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, according to a new study.
Cancer’s Most Deadly Assassin Exists in Every Cell
A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study.
Clues in Our Chromosomes
Understanding environmental factors helps scientists like cancer epidemiologist Lifang Hou, MD, PhD, chief of Cancer Epidemiology and Prevention in the Department of Preventive Medicine, detect the disease earlier.
New Insights Into Cancer Metastasis
Northwestern Medicine scientists have discovered how circulating tumor cells cluster together during metastasis — findings that reveal a novel mechanism for how cancer spreads and a potential new target for treatment.
Inherited Genetic Variants Associated With Bleeding on Common Anticoagulant
According to a recent study, a group of four gene mutations seen only in people with African ancestry may contribute to an increased risk of severe bleeding while taking warfarin.
Disrupting Gene Transcription Elongation to Treat Cancer
Targeting cancer cells with a transcription elongation inhibitor delayed tumor progression in animal models, according to a recent Northwestern Medicine study.