Tumor Mutations Predict Response to Immunotherapy
A recent Northwestern Medicine study found that patients with glioblastoma responded better or worse to immunotherapy depending on the presence of certain mutations in their tumors.
Browsing: "Genetics"
Gene Variants Associated With Tobacco and Alcohol Use Identified
Scientists identified over 500 genetic variants associated with tobacco or alcohol use, in a genome-wide association study recently published in Nature Genetics.
New Fragile X Genes Discovered
A genome-wide analysis revealed nine new genes associated with fragile X syndrome, findings that shed light on the complex hereditary mechanisms behind the genetic disease.
How Neutrophils Drive DNA Damage Linked to Cancer
Northwestern Medicine scientists demonstrated how innate immune cells in inflamed tissue induce DNA damage that promotes the development of cancer.
New Gene Associated With Glioblastoma Discovered
Northwestern Medicine scientists have identified a gene, called isocitrate dehydrogenase 3-alpha, that promotes tumors in grade IV glioblastoma, according to a study published in Science Advances.
McNally Elected to National Academy of Inventors
Elizabeth McNally, MD, PhD, has been elected as a fellow of the National Academy of Inventors, joining more than 900 other inventors, who were selected for prolific innovations that improve quality of life or economic development.
New Regulator of Leukemia Discovered
Inhibiting CHAF1B, a protein that normally helps replenish blood cells, may be a promising treatment for leukemia, according to a recent study.
Chromosome Domain Inherits Information Without Using DNA Sequence
A recent study found that stability of chromatin structures across DNA replication requires cooperation between a histone chaperone and DNA replication machinery; a mechanism of epigenetic inheritance.
Krainc Honored at American Neurological Association Meeting
Dimitri Krainc, MD, received the Soriano Award at the American Neurological Association (ANA) 143rd Annual Meeting.
Inherited Genetic Variants Associated With Bleeding on Common Anticoagulant
According to a recent study, a group of four gene mutations seen only in people with African ancestry may contribute to an increased risk of severe bleeding while taking warfarin.