How Neutrophils Drive DNA Damage Linked to Cancer
Northwestern Medicine scientists demonstrated how innate immune cells in inflamed tissue induce DNA damage that promotes the development of cancer.
Browsing: "Genetics"
New Gene Associated With Glioblastoma Discovered
Northwestern Medicine scientists have identified a gene, called isocitrate dehydrogenase 3-alpha, that promotes tumors in grade IV glioblastoma, according to a study published in Science Advances.
McNally Elected to National Academy of Inventors
Elizabeth McNally, MD, PhD, has been elected as a fellow of the National Academy of Inventors, joining more than 900 other inventors, who were selected for prolific innovations that improve quality of life or economic development.
New Regulator of Leukemia Discovered
Inhibiting CHAF1B, a protein that normally helps replenish blood cells, may be a promising treatment for leukemia, according to a recent study.
Chromosome Domain Inherits Information Without Using DNA Sequence
A recent study found that stability of chromatin structures across DNA replication requires cooperation between a histone chaperone and DNA replication machinery; a mechanism of epigenetic inheritance.
Krainc Honored at American Neurological Association Meeting
Dimitri Krainc, MD, received the Soriano Award at the American Neurological Association (ANA) 143rd Annual Meeting.
Inherited Genetic Variants Associated With Bleeding on Common Anticoagulant
According to a recent study, a group of four gene mutations seen only in people with African ancestry may contribute to an increased risk of severe bleeding while taking warfarin.
Disrupting Gene Transcription Elongation to Treat Cancer
Targeting cancer cells with a transcription elongation inhibitor delayed tumor progression in animal models, according to a recent Northwestern Medicine study.
Prindle Receives 2018 Packard Fellowship
Arthur Prindle, PhD, assistant professor of Biochemistry and Molecular Genetics, will study bacterial communication and its potential applications to human health with a five-year grant from The David and Lucile Packard Foundation.
Alzheimer’s Drug Shows Promise, But Risk Remains
An experimental genetic inhibitor that could stave off Alzheimer’s disease has unintended consequences, but may represent a target for future drug development, according to a recent study.