Mutations Synergize in Pediatric Brain Cancer
A new Northwestern Medicine study has demonstrated that a combination of two mutations makes a form of pediatric brain tumors more deadly.
Browsing: "Genetics"
New Metabolic Function of Protein Discovered
Northwestern scientists have identified a new function for a transcription factor called BCL6, finding that it switches off genes involved in lipid metabolism.
Male Hormone Gene Plays Major Role in Leading Cause of Female Infertility
A gene involved in male hormone production plays a major role in the development of polycystic ovary syndrome, according to a recent study.
Genetic Links to Asthma in People of African Ancestry
A team of scientists has identified new genetic regions associated with asthma in people of African ancestry, according to a study published in Nature Communications.
Tumor Mutations Predict Response to Immunotherapy
A recent Northwestern Medicine study found that patients with glioblastoma responded better or worse to immunotherapy depending on the presence of certain mutations in their tumors.
Gene Variants Associated With Tobacco and Alcohol Use Identified
Scientists identified over 500 genetic variants associated with tobacco or alcohol use, in a genome-wide association study recently published in Nature Genetics.
New Fragile X Genes Discovered
A genome-wide analysis revealed nine new genes associated with fragile X syndrome, findings that shed light on the complex hereditary mechanisms behind the genetic disease.
How Neutrophils Drive DNA Damage Linked to Cancer
Northwestern Medicine scientists demonstrated how innate immune cells in inflamed tissue induce DNA damage that promotes the development of cancer.
New Gene Associated With Glioblastoma Discovered
Northwestern Medicine scientists have identified a gene, called isocitrate dehydrogenase 3-alpha, that promotes tumors in grade IV glioblastoma, according to a study published in Science Advances.
McNally Elected to National Academy of Inventors
Elizabeth McNally, MD, PhD, has been elected as a fellow of the National Academy of Inventors, joining more than 900 other inventors, who were selected for prolific innovations that improve quality of life or economic development.