Northwestern is part of the Impact of Genomic Variation on Function (IGVF) Consortium, a $185 million National Institutes of Health (NIH) project that will explore the millions of genetic variants that cause disease around the world.
An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.
A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus.
Northwestern’s Brain Tumor SPORE — part of the Lurie Cancer Center — is now three years old, and the bench to bedside process is producing results.
Harmful side effects from a common chemotherapy drug could be prevented in patients with a specific mutation by targeting retinoic acid receptors, according to a recent study.
Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder.
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template.
Genomic autopsy of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy.
Losing a check on T-cell activation in cutaneous T-cell lymphoma cells is associated with poor outcomes, according to a study published in Blood.
Using circulating tumor DNA to identify patients at risk for urothelial cancer relapse after surgical resection could help improve post-surgery treatment, according to a new study.