New Method to Untangle 3D Cancer Genome
Northwestern Medicine scientists have described a method of reconstructing the three-dimensional structure of chromosomes in cancer cells and matching those chromosomes with counterpart oncogenes.
Browsing: "Genetics"
New Method to Analyze Nucleosomes
Northwestern Medicine scientists have developed Nuc-MS, a new method to capture the protein composition of whole nucleosomes without losing information.
Mitochondria Play Key Role in Lymphatic Development
Mitochondria play a key role in forming the lymphatic vasculature by acting as a metabolic sensor during the migration of lymphatic progenitor cells from the veins.
Uncovering the Function of Prostate Cancer Protein
Northwestern Medicine scientists have discovered a mechanism that makes a prostate cancer-causing protein called FOXA1 more resilient, according to a recent study.
The XX/XY Factor
A massive trove of information produced in a Northwestern-led study will lay the groundwork for understanding sex-related differences in health and disease for decades to come.
Next-Gen Sequencing
Northwestern’s investment in next-generation sequencing is leading to unprecedented avenues of discovery.
New Genetic Cause of Dystonia Revealed
Northwestern Medicine scientists discovered mutations in a scaffolding protein contributes to dystonia, an incurable movement disorder.
Predicting the Severity of Cardiomyopathy via Genetic Modifiers
A team of Northwestern Medicine investigators have identified specific genetic regions that regulate the expression of genes associated with inherited cardiomyopathy and disease severity.
Blocking Cell Division in Glioblastoma
Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.