New Chemotherapy Alternative for Lymphoma
A new immunotherapy treatment for recurrent B-cell lymphoma was found to be safe in a trial of nearly 350 patients, according to a study published in The Lancet.
Browsing: "Genetics"
New Drug Target for Treatment-Resistant Prostate Cancer
Inhibiting an epigenetic regulator called DOT1L could be a key to slowing treatment-resistant prostate cancer, according to a recent Northwestern Medicine study.
Biological Sex Affects Genes for Body Fat, Cancer, Birth Weight
Biological sex has a small but ubiquitous influence on gene expression in almost every type of human tissue, according to a new study.
Gene Therapy Could Treat Atrial Fibrillation
Targeting oxidative stress with a genetic therapy reduced atrial fibrillation in animal models of disease, making this a promising future treatment, according to a study published in Circulation.
Uncovering Similarities Between Prostate Cancer Genomes
Genomic alterations in prostate cancer therapeutic targets were found to be similar between African American and European American men, suggesting that existing precision medicine approaches could equally benefit both groups if applied equitably, according to a recent study.
New Machine-learning Method to Identify Chromatin Loops
A machine-learning program called Peakachu can reveal previously unknown chromatin loops, according to a Northwestern Medicine study published in Nature Communications.
AI-Enhanced Approach Offers New Hope for Earlier Autism Diagnoses
A Northwestern Medicine scientist and collaborators have used an AI-enhanced precision medicine approach to combine multiple views of human brain development as they seek to provide a roadmap for what causes subtypes of autism spectrum disorder.
Analyzing Plasma Can Classify Brain Tumors
Measuring epigenetic signatures in blood plasma could help classify brain tumors, according to a study published in Nature Medicine.
Protein May Improve Immunotherapy for Medulloblastoma
A specific cell signaling protein may be used to enhance the sensitivity of medulloblastoma tumors to immunotherapy, potentially improving quality of life for patients with the malignant pediatric brain cancer.
Critical Function of Cilia Protein Discovered
A protein gives motile cilia part of their structure, according to a recent Northwestern Medicine study.