Tag: Research
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Evaluating A Novel Chemo-free Combination Therapy for Lymphocytic Leukemia
A phase 1 clinical trial of venetoclax and rituximab combination therapy was shown to be an effective chemo-free treatment option for patients with difficult-to-treat chronic lymphocytic leukemia.
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Novel Biomarker Predicts Treatment Response in Chronic Leukemia
A newly identified biomarker may predict treatment response in patients with chronic myelogenous leukemia, according to a Northwestern Medicine study.
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Feinberg Research Retreat Brainstorms Transformation
Nearly 300 principal investigators gathered for a day of discussion and brainstorming to generate transformative ideas that will help guide the Feinberg research enterprise for the next five years.
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Understanding How Calcium Channels Open and Close
Northwestern Medicine scientists identified the process by which a calcium channel called the CRAC channel opens and closes, and how mutations in the channel structures that control its opening cause disease.
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Evaluating a Therapy for Rare Midgut Tumors
In recent Northwestern Medicine clinical trials, an experimental drug improved survival rates for patients with advanced midgut neuroendocrine tumors compared to a standard therapy.
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Insights Into Key Molecular Process Underlying Many Cancers
A paper published in Molecular Cell provides new insight into a protein complex called COMPASS and its function during histone methylation, a key modification that regulates gene expression.
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Uncovering Metabolism’s Clockwork
Joseph Bass, MD, PhD, chief of Endocrinology, Metabolism and Molecular Medicine, focuses his research on illuminating how the body’s clocks regulate feeding behavior and glucose metabolism, and identifies how disruptions in that overarching circadian system play a role in metabolic disease.
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Overexpression of Protein Improves Cardiac Efficiency
Northwestern Medicine scientists showed how the overexpression of the protein SNRK in cardiac tissue improves cardiac metabolism and is protective against ischemic conditions.
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Showcasing Integrative Medicine at Inaugural Osher Research Day
Northwestern Medicine scientists presented recent research findings in the field of integrative medicine at the first annual Osher Center Research Day.
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Investigating a Novel Pathology for ALS
A new review, published in Nature Reviews Neurology, outlines how upper motor neuron degeneration is an important feature in ALS pathology, and could be key to developing better diagnostic tools and treatments for ALS.
