Anti-Cancer Inhibitor Could Have Dual Effect
TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.
Browsing: "Research"
Lurie Cancer Center Receives Merit Extension from NCI
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a Merit Extension Award from the National Cancer Institute, one of only two Comprehensive Cancer Centers in the nation to earn the recognition.
For Every Man: Northwestern Investigators’ Critical Impact on Prostate Cancer
From teasing out determinants of health disparities to developing precision medicine treatments, clinicians and scientists from the Lurie Cancer Center are dramatically changing the landscape for all men with prostate cancer.
Study Identifies Expanded Role for Metabolic Enzyme in Kidney Cancer
The underexpression of a specific metabolic enzyme metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma, which accounts for 80 percent of all kidney cancers, according to a recent study.
Advancing Treatment for B-cell Acute Lymphoblastic Leukemia
Tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell immunotherapy, demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia, according to recent findings.
Three Feinberg Faculty Elected to National Academy of Medicine
Elizabeth McNally, MD, PhD; Melissa Simon, MD, MPH; and Guillermo Ameer, ScD; have been elected to the National Academy of Medicine.
Lewy Body Dementia Exacerbated by Immune Response
T-cells respond to buildup of alpha-synuclein with a harmful auto-immune response, according to a Northwestern Medicine study published in Science.
Machine-learning Model Can Detect Rare Cardiomyopathy
A machine learning model can identify patients at risk of a rare cardiomyopathy, according to a recent study.
Northwestern Scientists Explore Impacts of Genomic Variation in Disease in NIH Project
Northwestern is part of the Impact of Genomic Variation on Function (IGVF) Consortium, a $185 million National Institutes of Health (NIH) project that will explore the millions of genetic variants that cause disease around the world.
Skin Cancer Harbors Targetable Mutation
An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.