Tag: Research
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Identifying Patients at Lower Risk for Kidney Transplant Rejection
A new risk stratification model developed by Northwestern Medicine scientists may help better identify patients who have a lower risk of kidney transplant rejection, which can inform more personalized treatment and care strategies that present fewer adverse side effects, as detailed in a recent study published in Nature Communications.
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Investigating Tumor Growth After Immunotherapy
A new Northwestern Medicine study has uncovered a biological mechanism that may explain why a subset of tumors unexpectedly grows at an accelerated rate after being treated with certain immunotherapies, according to findings published in Cancer Discovery.
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Novel Spatial Technology May Improve the Understanding of Cancer Biology
Northwestern Medicine scientists have developed a novel high-resolution 3D spatial genomics platform that may enhance future research about how genome organization and genetic alterations contribute to the development of disease, including cancer, as detailed in a recent study published in Nature Methods.
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Experimental Drug May Disrupt Immune Circuits in Pneumonia
A drug that blocks calcium release-activated calcium channels may help interrupt harmful immune cell interactions that drive severe viral pneumonia, according to a new study published in The Journal of Clinical Investigation.
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Assessing the Benefit of Heart Calcium Scans
A new Northwestern Medicine study shows that a test known as a coronary artery calcium scan may be most valuable only for a specific group of patients.
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Targeting Protein Synthesis Control Regions May Reduce Seizures in Genetic Epilepsy
Targeting the control of protein synthesis in the KCNQ2 gene may serve as a potential disease-modifying strategy for patients with a genetic form of neonatal-onset epilepsy and impaired brain development, according to a Northwestern Medicine study published in Proceedings of the National Academy of Sciences.
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Extreme Heat Linked to 33 Diagnoses That Go Beyond Dehydration, Heat Stroke
A new Northwestern University study suggests that extreme heat is linked to a much wider range of health problems seen in emergency departments and urgent care clinics than previously expected.
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Loneliness Rewires the Brain to Drive Alcohol Consumption, Mouse Study Finds
Loneliness can reprogram the brain in ways that push alcohol consumption, reports a new preclinical study led by Northwestern University and the Salk Institute for Biological Studies.
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Enzyme Utilizes Specialized Mechanisms to Promote Cancer Cell Proliferation
A new Northwestern Medicine study has identified a previously unknown mechanism by which the NAT10 enzyme promotes cancer cell proliferation, establishing this protein as a promising therapeutic target for cancer.
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Designing Supramolecular Therapies to Cross the Blood-Brain Barrier
A new Northwestern Medicine study has uncovered key molecular design principles that could help supramolecular therapeutics cross the blood-brain barrier, a major challenge for the novel approach to treating neurological disorders.
