Tag: Genetics
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Uncovering Similarities Between Prostate Cancer Genomes
Genomic alterations in prostate cancer therapeutic targets were found to be similar between African American and European American men, suggesting that existing precision medicine approaches could equally benefit both groups if applied equitably, according to a recent study.
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New Machine-learning Method to Identify Chromatin Loops
A machine-learning program called Peakachu can reveal previously unknown chromatin loops, according to a Northwestern Medicine study published in Nature Communications.
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AI-Enhanced Approach Offers New Hope for Earlier Autism Diagnoses
A Northwestern Medicine scientist and collaborators have used an AI-enhanced precision medicine approach to combine multiple views of human brain development as they seek to provide a roadmap for what causes subtypes of autism spectrum disorder.
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Analyzing Plasma Can Classify Brain Tumors
Measuring epigenetic signatures in blood plasma could help classify brain tumors, according to a study published in Nature Medicine.
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Protein May Improve Immunotherapy for Medulloblastoma
A specific cell signaling protein may be used to enhance the sensitivity of medulloblastoma tumors to immunotherapy, potentially improving quality of life for patients with the malignant pediatric brain cancer.
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Critical Function of Cilia Protein Discovered
A protein gives motile cilia part of their structure, according to a recent Northwestern Medicine study.
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Chimeric Toxin Slows Cancer Growth
A novel compound using diphtheria toxin to attack a signaling pathway implicated in as many as 50 percent of cancers slowed tumor growth, according to a recent study.
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New Role for RNA Splicing in Insulin Regulation
The gene transcription machinery that controls circadian rhythms also regulates insulin release in the pancreas, according to a Northwestern Medicine study.
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New Genetic Regulators Could Improve Cancer Immunotherapy
A genetic screen has revealed previously unknown regulators of Foxp3, a transcription factor that, when deactivated, may improve patient response to aggressive cancers.
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New Insights into Left Ventricular Cardiomyopathy
Genetic mutations in desmoplakin cause left ventricular cardiomyopathy, rather than right ventricular cardiomyopathy as previously believed, according to a recent study.
