Tag: Research
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Intercellular Mechanisms Regulate Gene Expression in Cancer Cells
Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according to a Northwestern Medicine study published in Molecular Cell.
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Investigators Discover New Therapeutic Target for Pediatric Brain Cancers
Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
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Intense Exercise Doesn’t Increase Risk of Sudden Death in Genetic Heart Disorder
High-intensity exercise does not increase the risk of sudden cardiac death in individuals with congenital long-QT syndrome, a genetic heart disorder, according to findings from a recent study published in Circulation.
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Study Identifies Racial Differences in Rare Endometrial Cancer
Northwestern Medicine investigators have discovered that uterine serous carcinoma tumors in Black patients express more aggressive and immunosuppressive features than tumors in white patients, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Understanding Epigenetic Control of Antibody Responses
Northwestern Medicine investigators have uncovered how antibody responses are regulated by epigenetic factors commonly mutated in cancers, according to a study published in Nature Immunology.
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‘Hidden’ Irregular Heartbeats May Raise Risk of Death
Irregular heartbeats can raise a person’s risk of death even when they go unnoticed by traditional heart monitoring, according to a Northwestern Medicine study published in Circulation.
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Analyzing the Effects of Dietary Acculturation on Heart Health
Dietary acculturation may increase the risk of heart disease for people of Hispanic or Latino heritage in the U.S., according to a study published in Circulation.
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‘Feedback Loop’ Promotes Cancer Cells’ Adaption to Molecular Stress
Investigators from the laboratory of Marc Mendillo, PhD, have discovered new cellular regulators of an established cancer cell transcription factor linked to cancer cell resilience and tumor progression, according to findings published in the Proceedings of the National Academy of Sciences.
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Novel AI Model May Enhance Health Data Interoperability
An AI model developed by Northwestern Medicine investigators improved the transformation of EHR data into standardized health resources more efficiently than current methods, according to a recent study published in journal NEJM AI.
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Summer Research Program Trains Future Clinician-Scientists
Eight Feinberg medical students recently participated in a summerlong research program designed to equip them with the skills to become successful clinician-scientists.
