Tag: Pharmacology
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Low Dose Beta-Blockers As Effective As High Dose After a Heart Attack
In a new study, patients treated with one-fourth of the dose of beta-blockers tested in large clinical trials had a 20 to 25 percent increase in survival, indicating that dosing likely needs to be personalized for patients to get the best benefit.
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Tracking the Immune Response to Flu Virus
A trail of messenger molecules left behind by general immune system cells called neutrophils helps virus-specific T-cells reach tissues infected by influenza, reports a new study published in Science.
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Research Will Determine Optimal Antidepressant Drug Doses During Pregnancy
Northwestern Medicine scientists received a five-year, $3.9 million grant from the National Institutes of Health to determine the optimal drug doses for treating pregnant women with depression.
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Sorting Proteins for Cell Communication
Northwestern Medicine scientist Jeffrey Savas, PhD, and colleagues identified a receptor that sorts proteins in synapses, a finding that may augment future treatments for multiple neurological diseases and disorders.
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Mechanisms Behind Mutations in Calcium Ion Channels and Immunodeficiency
Northwestern Medicine scientists investigated the mechanism behind a mutation in a calcium ion channel that leads to an immunodeficiency syndrome.
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Healing Plants Inspire New Compounds For Psychiatric Drugs
Northwestern Medicine scientists, inspired by treatments used by traditional healers in Nigeria, have synthesized four new chemical compounds that may lead to therapies for psychiatric disorders.
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Sexual Dysfunction Inadequately Reported In Hair Loss Drug Trials For Men
Male baldness clinical trials did not adequately report sexual dysfunction, which may persist long-term, according to a Northwestern Medicine meta-analysis of published reports of clinical trials of the drug finasteride.
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Evaluating Drugs to Improve Vision In Diabetic Macular Edema
A new Northwestern Medicine study published in the New England Journal of Medicine shows the drug Eylea is superior to other options for improving the eyesight of persons with poor vision due to diabetic macular edema, a major cause of diabetes-related vision loss.
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Grant Funds Classification of Disease-Causing Genetic Mutations
A $5 million grant from the National Institutes of Health will support research to determine the functional and structural consequences of genetic mutations associated with a dangerous heart condition.
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Calcium Channel Discovery Unlocks Brain Therapy Options
Scientists from Northwestern Medicine have discovered a key function for the CRAC channel, which transports calcium into cells.
