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Home » Pharmacology

Browsing: Pharmacology

Disease Discoveries
Jun 5, 2023

Newly Discovered Mechanisms Increase Chemotherapy Resistance in Breast Cancer 

Northwestern Medicine investigators have discovered novel features of circulating tumor stem cells that can promote chemotherapy evasion and metastasis in triple-negative breast cancer, according to a recent study.

Scientific Advances
May 11, 2023

Improving the Study of Sex-Based Differences in Complex Traits and Disease 

Investigators led by Barbara Stranger, PhD, associate professor of Pharmacology, developed a guide outlining best practices for studying and testing sex-dependent genetic effects in complex traits and diseases, published in the journal Cell.

Scientific Advances
Feb 7, 2023

Genetic Variations Influence Drug Metabolism in Patients of African Descent

Northwestern Medicine investigators have identified new genetic variations effecting gene expression in the liver cells of patients of African descent, findings that provide insight into how drugs are metabolized differently in different populations.

Disease Discoveries
Feb 6, 2023

Potential Therapeutic Target for Schizophrenia Identified 

Targeting calcium signaling in neurons may represent a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study.

Scientific Advances
Jan 27, 2023

Calcium Channels Regulate Neuroinflammation and Neuropathic Pain 

Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain.

Clinical Breakthroughs
Dec 26, 2022

Northwestern Investigators Develop New Therapy for Autism Subtype

A team of Northwestern investigators led by Peter Penzes, PhD, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder.

Scientific Advances
Oct 27, 2022

Improving the Design of New Protein Structures

Northwestern Medicine investigators have developed a novel approach for designing and testing new protein folds, which could be used to develop new therapeutics.

Disease Discoveries
Oct 14, 2022

Newly Identified Protein Drives Breast Cancer Stemness and Metastasis

Using machine learning, Northwestern scientists have demonstrated that the protein membrane CD81 interacts with CD44 in promoting tumor cell cluster formation and lung metastasis of triple negative breast cancer.

Scientific Advances
Oct 4, 2022

Targeting Ion Channels to Manage Osteoarthritis Pain

Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy for managing osteoarthritis pain, according to a Northwestern Medicine study.

Scientific Advances
Aug 5, 2022

‘Inside Out’ Signaling Promotes Tumor Growth

An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.

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Latest News

Biological Aging Increases Risk of Depression, Anxiety in Adults 

Jun 7, 2023

Developing New Nanoparticle Treatments for Brain Tumors

Jun 6, 2023

Newly Discovered Mechanisms Increase Chemotherapy Resistance in Breast Cancer 

Jun 5, 2023

Improving Cancer Detection for Women with Dense Breasts

Jun 5, 2023

Transcription Factor Prevents Bone Frailty in Chronic Kidney Disease

Jun 2, 2023
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