African Ancestry Affects Gene Expression
Levels of African ancestry in a person’s genome determines the level at which certain genes are expressed, findings that could offer insight into the different risk of diseases.
Browsing: "Pharmacology"
Experimental Drug May Reduce Cancer Growth and Progression
Scientists co-led by Sui Huang, MD, PhD, found an experimental drug called metarrestin significantly reduced metastasis and cancer progression in mouse models.
Expanding Genetic Screening Guidelines for Colon Cancer
A new study provided evidence that current guidelines for genetic screenings for colorectal cancer-associated genes are missing patients and should be expanded.
Scientists Discover Unexpected Functions of Neural Protein
A new study identified two new functions of a neural regulatory protein, with possible clinical implications down the line.
Exploring the Molecular Mechanisms of Ion Channels and Kidney Disease
Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
Study Demonstrates How the Brain Moves Neuroreceptors
Northwestern Medicine scientists identified the mechanism that transports important neuroreceptors from sites outside to within the synapse, publishing their findings in Cell Reports.
Uncovering Enzyme’s Dual Role in Cancer Suppression and Growth
A new Northwestern Medicine study has uncovered how a key enzyme in mitochondria can function as both a cancer suppressor and cancer promoter.
Calcium Channels Play Essential Role in Astrocyte Activity
Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.
Scientists Identify Function of Alzheimer’s Protein
A team of scientists has discovered the physiological function of APP, a protein long known to be associated with Alzheimer’s disease but whose normal function had remained elusive.
New Inhibitor Improves Autism-Like Symptoms in Mice
A Northwestern University experimental therapeutic targeting a specific protein kinase reversed neurological symptoms in a mouse genetic model of autism, according to a recent Northwestern Medicine study.