Browsing: Pharmacology

A team of Northwestern investigators led by Peter Penzes, PhD, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder.

Northwestern Medicine investigators have developed a novel approach for designing and testing new protein folds, which could be used to develop new therapeutics.

Using machine learning, Northwestern scientists have demonstrated that the protein membrane CD81 interacts with CD44 in promoting tumor cell cluster formation and lung metastasis of triple negative breast cancer.

Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy for managing osteoarthritis pain, according to a Northwestern Medicine study.

An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.

Designed to target AMPAR receptors in the brain, the medication — called perampanel — also modulates kainate receptors.

An enzymatic modifier of messenger RNA has different functions depending on its location, according to a recent study.

A subunit of voltage-gated calcium channels was found to have a functional role in T-cells, according to a study published in Nature Communications.

Higher doses of anti-seizure medications may be necessary during pregnancy, according to a recent study.

Northwestern Medicine scientists discovered functional links between dozens of potassium channel gene variants and neonatal epilepsy.