Northwestern Medicine scientists have identified the unique targets of two enzymes that activate ubiquitination, a key modification of proteins that controls a variety of cellular processes.
A novel national trial for people with no established alternative to treat their rare cancers is being co-led by Northwestern Medicine investigators, who helped conceive of and develop the project.
The addition of the drug cetuximab to standard chemoradiation reduced the incidence of relapse for patients with anal cancer, but was associated with significant adverse effects, according to recent Northwestern Medicine clinical trials.
A recent clinical trial assessed the efficacy and safety of the drug ibrutinib in patients with Waldenstrom’s macroglobulineaemia, a type of non-Hodgkin lymphoma, who were not responding to other treatments.
Northwestern Medicine scientists have identified a molecular therapy to prevent the growth of a rare pediatric leukemia.
A recent study explores the use of metabolic markers to target ovarian cancer stem cells and could improve outcomes of existing therapies.
Northwestern’s Cancer Survivorship Institute addresses the medical, psychological and social challenges patients face after their cancer is gone.
Northwestern University synthetic biologists have developed a general method for “rewiring” immune cells to help overcome immunosuppression in cancer.
A new strategy for targeting a protein called GRP78 could be used to simultaneously provide diagnostic imaging and deliver treatment for inflammatory breast cancer, according to a recent study.
Two HIV-associated cancers are less common since the advent of antiretroviral therapy, but still occur in patients with controlled HIV, according to a Northwestern Medicine study.