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Newly Discovered Mechanisms Increase Chemotherapy Resistance in Breast Cancer
Northwestern Medicine investigators have discovered novel features of circulating tumor stem cells that can promote chemotherapy evasion and metastasis in triple-negative breast cancer, according to a recent study.
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Improving Cancer Detection for Women with Dense Breasts
The use of ultrasound screening and 3D mammography only slightly increases the detection rate of breast cancer in women with dense breasts, according to a prospective multicenter study published in the Journal of Clinical Oncology.
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Transcription Factor Prevents Bone Frailty in Chronic Kidney Disease
Northwestern Medicine investigators have discovered that the overexpression of a specific transcription factor prevented bone loss in mouse models with complications from chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation.
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Study Establishes Fluctuating ’Gating’ Mechanisms Supporting Flexible Behavior
A study led by Elizabeth Johnson, PhD, has established fluctuating “gating” mechanisms that support flexible behavior and working memory in humans, findings recently published in Nature Communications.
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Discussing New Frontiers in Biomedicine
An expert panel of Northwestern leaders recently explored hot topics in longevity, AI, regenerative medicine, bioelectronics and new approaches to cancer treatment.
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Reducing Seizures After Brain Tumor Treatment
Northwestern Medicine investigators have shown that inhibiting a mutated gene can reduce seizure activity in adult-type diffuse gliomas, according to a study published in the Journal of Clinical Investigation.
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Northwestern Accepting Nominations for $350,000 Nemmers Prize in Medical Science
Northwestern University is accepting nominations for its $350,000 Mechthild Esser Nemmers Prize in Medical Science.
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Genetic Mutation Responsible for Rare Neurodevelopmental Disorder Identified
Using zebrafish models, investigators have discovered that MAP4K4 genetic variants cause neurodevelopmental delays and other physical abnormalities, demonstrating a potential therapeutic target for treating the disorder in humans, according to findings published in Science Advances.
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Celebrating Advances in Alzheimer’s Research and Clinical Care
Attendees gathered on May 11 for Alzheimer Day, an annual event hosted by the Mesulam Center for Cognitive Neurology and Alzheimer’s Disease to showcase dementia and aging research conducted throughout Northwestern and bring those discoveries to the community.
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Understanding How Hormones Influence Anemia
Northwestern Medicine scientists have uncovered how peptides produced by bones during inflammation prevent anemia in mice, according to a recent study published in the journal Blood.
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Groundbreaking Geneticist Delivers Epigenetics Lecture
Huda Yahya Zoghbi, MD, the inaugural winner of the 2016 Mechthild Esser Nemmers Prize in Medical Science at Northwestern University, returned to Feinberg on Monday as part of the Simpson Querrey Institute for Epigenetics Distinguished Lecturer Series.
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CT Scan Best at Predicting Heart Disease Risk in Middle Age
CT scans are better at predicting a middle-aged person’s risk for a heart disease, such as a heart attack, than genetics, reports a new Northwestern Medicine study published in JAMA.
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Investigating the Benefits of Salt Substitutes in Elderly Patients
Salt substitutes may be effective in lowering blood pressure and reducing cardiovascular events in residents of elderly care facilities, according to a recent multi-center study published in Nature Medicine.
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Understanding How Aggressive Thyroid Cancer Evolves
Northwestern Medicine scientists have shed new light on how the deadliest form of thyroid cancer becomes more aggressive, according to research published in the Journal of Clinical Investigation.
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Study Reveals Striking Excess Deaths for Black Americans Over Last 20 Years
From 1999 through 2020, Black Americans experienced more than 1.6 million excess deaths and more than 80 million excess years of life lost compared to white Americans, according to a recent study published in JAMA.
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Investigators Identify Mechanisms Behind Chemotherapy Resistance
A team led by Northwestern Medicine investigators have discovered novel cellular mechanisms that lead to chemotherapy resistance in recurrent glioblastoma, according to findings published in Science Advances.
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Honoring the MD Class of 2023
Feinberg honored the MD Class of 2023 during the medical school’s 164th commencement ceremony in the Aon Grand Ballroom at Navy Pier.
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Honors Day Celebrates Student and Faculty Excellence
Faculty members and fourth-year medical students were recognized for their academic and clinical excellence during Feinberg’s Honors Day, held May 12 in the Hughes auditorium.
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Increasing Early Cardiovascular Screenings for Dilated Cardiomyopathy
An informational communications tool provided to patients with dilated cardiomyopathy helped increase cardiovascular screenings in their first-degree relatives who have a higher risk of developing the genetic disease, according to findings published in Circulation.
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Improving the Study of Sex-Based Differences in Complex Traits and Disease
Investigators led by Barbara Stranger, PhD, associate professor of Pharmacology, developed a guide outlining best practices for studying and testing sex-dependent genetic effects in complex traits and diseases, published in the journal Cell.
