Category: Disease Discoveries
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New Method Tests Effectiveness of MS Treatments
Northwestern Medicine scientists created a more objective, precise and quicker way to test the effectiveness of multiple sclerosis drugs that may promote the repair of myelin, a protective sheath on neurons.
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Genetic Mutations Linked to Severe Epilepsy
Northwestern Medicine scientists discovered that genetic mutations in the KCNB1 potassium channel gene can result in severe early onset epilepsy.
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Stopping Tumor Growth During Hypoxia
Inhibiting a ubiquitin ligase stops tumor growth during hypoxia, a common characteristic of lung and brain cancers.
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New Understanding of Cystic Fibrosis Gene Expression
Nehal Gosalia, ’14 PhD, examined the role of architectural proteins in regulation of expression of the cystic fibrosis gene.
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Detecting Early Stage Knee Osteoarthritis
Northwestern Medicine scientists found that lesions seen in MRIs of knees without any x-ray signs of osteoarthritis predict the development of persistent symptoms of the disease and the first appearance of cartilage damage.
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A New Way to Prevent Organ Transplant Rejection
Northwestern Medicine scientists discovered a method to promote organ transplant tolerance by limiting the immune response in a novel way.
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Scientists Develop First Animal Model for ALS Dementia
Northwestern Medicine scientists have developed the first animal model for ALS dementia, a form of ALS that also damages the brain, allowing for direct monitoring of test drugs to determine if they work.
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First Blood Test to Diagnose Depression in Adults
Northwestern Medicine scientists developed the first blood test to diagnose major depression in adults and to predict who will benefit from cognitive behavioral therapy.
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Pathway Found for Treating Fatal Lung Disease
Northwestern Medicine scientists identified genes correlated with the progression and severity of idiopathic pulmonary fibrosis.
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New Insights for Therapeutic Intervention in Melanoma
Mary J.C. Hendrix, PhD, revealed a variance in signaling pathways in embryonic stem cells and metastatic melanoma cells that may impact new therapeutic strategies in cancer.
