Marcus Peter, PhD, professor in Medicine-Hematology/Oncology, has discovered how the removal of a known “tumor suppressor” causes cancer cells to kill themselves.
Chair of Obstetrics and Gynecology says discovery will help scientists understand one of the major causes of female infertility.
Part of the $8 million multinational TumAdoR project, the study investigates the CD73 enzyme, which is overexpressed in many different forms of the disease.
Christian Stehlik and colleagues have learned how the molecular sensors that detect viruses and trigger defensive inflammatory responses are controlled.
The technique, used to measure blood flow in the heart and vessels, can also diagnose bicuspid aortic valve, a common congenital abnormality, and may lead to better prediction of complications.
Elevated blood pressure as young as age 18 is a warning sign of cardiovascular disease developing later in life and the time to begin prevention. That’s decades earlier than clinicians and patients generally start thinking about heart disease risk.
The discovery of an enzyme that is highly activated in cells from the joint fluid of rheumatoid arthritis patients may provide a new therapeutic target for the 1 million Americans affected by the disease.
Anis Contractor, PhD, associate professor in Physiology, recently published findings on what causes delays in synaptic and neuronal development in the cortex, hallmarks of fragile X syndrome, the most common known cause of autism.
Hossein Ardehali, MD, PhD, has discovered that doxorubicin, an effective and commonly used anticancer drug, is causing an accumulation of iron inside of a cell’s mitochondria, resulting in heart damage.
After a heart attack, much of the damage to the heart muscle is caused by inflammatory cells that rush to the scene of the oxygen-starved tissue. But the damage is slashed in half when microparticles are injected into the blood stream within 24 hours of the attack, according to preclinical research.
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