Category: Disease Discoveries
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Target Identified to Inhibit Prostate Cancer Cells
Prostate cancer cells producing too much PIM1 are particularly sensitive to the inhibition of a protein called polo-like kinase (PLK1).
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Air Pollution Shown to Increase Lung Inflammation and Blood Clots
Northwestern Medicine scientists demonstrate that exposure to air pollution causes a stress response characterized by elevation in the level of the stress hormone adrenaline.
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The Role of Signaling Pathways in Painful Diabetic Neuropathy
Daniela Menichella, MD, PhD, assistant professor in Neurology, studies the mechanism and role of the protein chemokine SDF-1 and its receptor CXCR4 in Painful Diabetic Neuropathy.
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Study Helps Explain Chronic Inflammation in Colon Cancer
Scientists from Northwestern Medicine and the University of Chicago identified elevated levels of a regulatory protein called beta-catenin in the T-cells of patients with colon cancer.
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Investigating Follicle Development
Robin Skory, an MD/PhD student, worked in the lab of Teresa Woodruff, PhD, to study follicle development and fertility preservation.
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New Role for Caspase-8 in Dendritic Cells
An enzyme called caspase-8 prevents the onset of autoimmune disease lupus when expressed by dendritic cells.
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Finding Offers Insight into Rare Childhood Disease that Affects Breathing
Northwestern Medicine scientists have discovered that children with a rare breathing disorder have a diminished rather than absent response to changes in oxygen and carbon dioxide levels within their bloodstream. The finding was recently published in the Journal of Applied Physiology.
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Scientists Find Heart Disease Can Be Reversed by Adopting Healthy Habits
Northwestern Medicine study found when adults in their 30s and 40s drop unhealthy habits they can potentially reverse the natural progression of coronary artery disease.
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Study Finds Sex-Specific Differences in Chronic Rhinosinusitis
Kathryn E. Hulse, PhD, research assistant professor in Medicine-Allergy-Immunology, found that while men are more likely to have chronic rhinosinusitis with nasal polyps, women with the disease have a more severe form.
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Carotid Artery May Hold Clues to Predicting CVD in Lupus
Rosalind Ramsey-Goldman, MD, professor of Medicine-Rheumatology, recently published a paper in the American Journal of Cardiology that links plaque in the carotid artery of women with lupus to an increased risk of cardiovascular events.
