Northwestern Medicine scientists demonstrated the ability of a protein, Cas2, in Legionella pneumophila to cleave nucleic acids resulting in increased infectivity in amoebae, its host organism and transmission vehicle for human infection of Legionnaires’ disease.
Northwestern Medicine scientists identified bacteria genes and key factors that are required for host colonization in squid, which may lead to better understanding how humans develop symbiotic relationships with beneficial bacteria.
Northwestern Medicine scientists created a more objective, precise and quicker way to test the effectiveness of multiple sclerosis drugs that may promote the repair of myelin, a protective sheath on neurons.
Northwestern Medicine scientists uncovered a molecular mechanism behind the regulation of the immune system in the gut.
Scientists used a new technique, fast photochemical oxidation of proteins, to better understand how enveloped viruses infect host cells.
Hyewon Phee, PhD, assistant professor in Microbiology-Immunology, showed that a lack of the protein Pak2 in immune cells may lead to immunodeficiency in patients.
Celeste Mallama, a fourth-year graduate student, studies how the bacterium that causes Legionnaires’ Disease infects host cells.
Kamonwan Pear Fish, a PhD/MPH student, uses mouse models to study how a viral protein from the Epstein Barr Virus can disrupt cell function and accelerate tumor growth.
Published in mBio, the findings offer the first evidence that seminal plasma may have a direct role in promoting the transmission of a sexually transmitted infection.
Jennifer Heller, a fifth-year PhD candidate, uses animal models of colitis to better understand how the adaptive immune system becomes dysregulated.