Tag: Cancer
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Identifying Therapeutic Targets for B-cell Acute Lymphoblastic Leukemia
Northwestern Medicine investigators have identified a protein kinase called DYRK1A and its downstream substrates as potential therapeutic targets for treating pediatric patients with B-cell acute lymphoblastic leukemia.
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Antibody Drug Improves Survival for Aggressive Breast Cancer
A new antibody drug demonstrated similar efficacy to currently available therapies to treat advanced ERBB2-positive breast cancer, according to a recent clinical trial.
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Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
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Uncovering How Protein Complexes Impact Gene Expression
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
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Why Black Men’s Prostate Cancer May be More Responsive to Immunotherapy
A new Northwestern Medicine study has discovered why Black men die more often of prostate cancer yet also have greater survival benefits from immunotherapy treatments.
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Study Identifies New Potential Therapeutic Approach for Glioblastoma
Northwestern Medicine investigators have identified a potential combined targeted therapy approach for treating glioblastoma, according to a recent study published in the journal Scientific Reports.
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Improving Treatment for Triple-Negative Breast Cancer
A team led by Northwestern Medicine investigators has identified a novel molecular target that may improve the efficacy of current treatments for triple-negative breast cancer.
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2020: A Year of Groundbreaking Discoveries During a Pandemic
Take a look back at a handful of groundbreaking research discoveries that marked one of, if not the most, unprecedented and transformative years for Feinberg.
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Streamlining Chemical-Genetic Screening
Northwestern Medicine scientists have developed a new high-throughput sequencing tool to test how drugs interact with genetically modified cells.
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Discovering New Mechanisms in Epigenetics
A series of recent discoveries by Northwestern Medicine scientists point to a more nuanced understanding of how epigenetic regulators function.
