Search results for: “shilatifard+published”
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Identifying Mechanisms of Methylation in Stem Cells
Northwestern Medicine scientists identified critical regulatory processes that govern differentiation in embryonic stem cells.
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Protein ‘Chaperone’ Plays Dual Role in DNA Replication
The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.
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Histone Protein Influences Both Neurological Disorder and Cancer
Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
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Northwestern Selected as Home for Journal of Clinical Investigation; McNally to Serve as Editor-in-Chief
Northwestern University Feinberg School of Medicine has been selected to serve as the home of the Journal of Clinical Investigation for its next five-year term, and Elizabeth McNally, MD, PhD, has been elected as the journal’s next editor-in-chief.
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Study Shows Epigenetic Modification is Central for Tumor Metastasis
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
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Three Feinberg Faculty Elected to National Academy of Medicine
Elizabeth McNally, MD, PhD; Melissa Simon, MD, MPH; and Guillermo Ameer, ScD; have been elected to the National Academy of Medicine.
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Transcription Elongation Checkpoint Discovered
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template.
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Uncovering Epigenetic Mechanisms Regulating Glioma Growth
Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of two oncogenes in glioma cells, which may improve personalized approaches to treat these cancers.
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3D Genome Structure Influences Cancer
For the first time, scientists have examined how the three-dimensional structure of chromatin can play a part in the development of bladder cancer and pediatric brain tumors, according to a pair of Northwestern Medicine studies.
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Identifying New Targeted Therapy Approaches for Leukemia
Using small molecular inhibitors to block the BAP1 complex may be a promising targeted therapy approach for leukemia, according to a Northwestern Medicine study published in Nature Cancer.
