Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of two oncogenes in glioma cells, which may improve personalized approaches to treat these cancers.
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For the first time, scientists have examined how the three-dimensional structure of chromatin can play a part in the development of bladder cancer and pediatric brain tumors, according to a pair of Northwestern Medicine studies.
Using small molecular inhibitors to block the BAP1 complex may be a promising targeted therapy approach for leukemia, according to a Northwestern Medicine study published in Nature Cancer.
Northwestern Medicine scientists have developed Nuc-MS, a new method to capture the protein composition of whole nucleosomes without losing information.
Northwestern Medicine investigators are advancing the understanding of two groups of transcription factors and their role in many neurodevelopmental diseases and cancers, which is essential for developing novel therapeutic approaches.
Several Feinberg faculty members have been elected to the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP).
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
A series of recent discoveries by Northwestern Medicine scientists point to a more nuanced understanding of how epigenetic regulators function.
A newly discovered function of an epigenetic regulator could be a key to new cancer treatments, according to a new study published in Genes and Development.
As the COVID-19 pandemic continues, recent editorials published by Feinberg faculty explore COVID-19 and its impact on medicine, including potential drug targets and the need for more clinical trials to maximizing trainee education.