An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, according to a new study.
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A new study has identified a molecular switch, through a protein called CDK9, that plays an early and critical role in the skin stem cell differentiation process.
Northwestern Medicine investigators have discovered novel mechanisms underlying transcription elongation, the process of synthesizing RNA from DNA.
Northwestern Medicine scientists identified critical regulatory processes that govern differentiation in embryonic stem cells.
The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.
Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
Northwestern University Feinberg School of Medicine has been selected to serve as the home of the Journal of Clinical Investigation for its next five-year term, and Elizabeth McNally, MD, PhD, has been elected as the journal’s next editor-in-chief.
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
Elizabeth McNally, MD, PhD; Melissa Simon, MD, MPH; and Guillermo Ameer, ScD; have been elected to the National Academy of Medicine.
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template.