New Epigenetic Regulation of Cancer Uncovered
Scientists have identified a new gene that can inhibit a multi-protein complex, possibly increasing the risk of cancer, according to a new study published in Science Advances.
Search Results: shilatifard+published (32)
Pediatric Leukemia ‘Super Drug’ Could be Developed in Coming Years
Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, the first step towards a pediatric leukemia “super drug.”
New Regulator of Leukemia Discovered
Inhibiting CHAF1B, a protein that normally helps replenish blood cells, may be a promising treatment for leukemia, according to a recent study.
Celebrating Our 2018 Discoveries
From fundamental new understandings of the cell published in Nature to landmark clinical trials in the New England Journal of Medicine and cross-disciplinary collaborations in Science Translational Medicine, investigators throughout our institution have advanced new knowledge that is already transforming their diverse fields.
Epigenetics: Landscape of Disease
The Simpson Querrey Center for Epigenetics is connecting the Northwestern academic and medical community to integrate the study of epigenetics into science and clinical care.
Disrupting Gene Transcription Elongation to Treat Cancer
Targeting cancer cells with a transcription elongation inhibitor delayed tumor progression in animal models, according to a recent Northwestern Medicine study.
3-D Structure of COMPASS Protein Complex Revealed
The three-dimensional atomic structure of the epigenetic driver COMPASS was solved for the first time in a study published in the journal Cell.
Shilatifard Named Editor of Science Advances
Ali Shilatifard, PhD, has been appointed editor of Science Advances, an open-access journal published by the American Association for the Advancement of Science, which also publishes the journal Science.
Resetting the Epigenetic Balance for Cancer Therapy
Northwestern Medicine scientists have discovered an epigenetic imbalance that can lead to cancer, and used these findings to inhibit tumors in models.
A New Weapon Against Cancer Metastasis
Northwestern Medicine scientists have discovered a new compound that halts the spread of multiple types of cancer cells.