A transcription factor protein may play an important role regulating genomic imprinting, a phenomenon where one of the two gene copies inherited from parents is silenced.
Marcus Peter, PhD, professor of Medicine in the Division of Hematology/Oncology, and Ali Shilatifard, PhD, chair of Biochemistry and Molecular Genetics, and Maciej Lesniak, MD, chair of Neurological Surgery, have each been awarded seven-year, $6.4 million grants from the National Cancer Institute.
Northwestern Medicine scientists have identified the molecular machinery that releases paused gene expression, a finding that helps explain how important developmental genes jumpstart simultaneously.
In several recent publications, Ali Shilatifard, PhD, chair of Biochemistry and Molecular Genetics, examined how different aspects of transcriptional regulation are involved in cancer development.
“For the medical school, 2014 was a tremendous year,” said Eric G. Neilson, MD, vice president for medical affairs and Lewis Landsberg Dean. A collection of stories spotlight some of the notable moments from the past year.
Ali Shilatifard, PhD, Chair of Biochemistry and Molecular Genetics, was appointed to the senior editorial board of the scientific journal Science. In his new role, he will provide strategic advice and constructive feedback about the journal.
Northwestern Medicine scientists have discovered a new potential drug therapy for pediatric brainstem glioma by targeting a genetic mutation found in patients with the rare, incurable cancer.
Ali Shilatifard, PhD, has been named the Robert Francis Furchgott Professor of Biochemistry and the Chairman of the Department of Biochemistry and Molecular Genetics.