Browsing: Pharmacology

In the past decade, synthetic biology — the reengineering of organisms and their genetic information so they can produce a new substance or gain a new ability — has rapidly emerged to the forefront of modern-day science. Northwestern’s Center for Synthetic Biology has been leading the way.

A Northwestern Medicine study has uncovered the molecular mechanisms behind the development of autosomal dominant polycystic kidney disease (ADPKD) and a potential drug target.

Levels of African ancestry in a person’s genome determines the level at which certain genes are expressed, findings that could offer insight into the different risk of diseases.

Scientists co-led by Sui Huang, MD, PhD, found an experimental drug called metarrestin significantly reduced metastasis and cancer progression in mouse models.

A new study provided evidence that current guidelines for genetic screenings for colorectal cancer-associated genes are missing patients and should be expanded.

A new study identified two new functions of a neural regulatory protein, with possible clinical implications down the line.

Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.

Northwestern Medicine scientists identified the mechanism that transports important neuroreceptors from sites outside to within the synapse, publishing their findings in Cell Reports.

A new Northwestern Medicine study has uncovered how a key enzyme in mitochondria can function as both a cancer suppressor and cancer promoter.

Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.