Tag: Pharmacology
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Deploying Polygenic Risk Scores in Primary Care Settings
A multi-institutional team of investigators have developed a new framework for supporting healthcare providers in implementing polygenic risk score-based testing into primary care settings, according to a recent study published in Nature Medicine.
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Uncovering the Mysteries of Microproteins
Northwestern Medicine scientists have developed a method to identify and characterize microproteins, a development which opens the door for understanding physiology and disease at a molecular level not possible until now, according to findings published in Nature Communications.
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Engineered Heart Cells May Improve Understanding of Atrial Fibrillation
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
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Novel Pathway Explains the Escalation of Fear Responses
Scientists have discovered a neuronal pathway involved in how the brain encodes the transition to high-intensity fear response behaviors required for survival, according to a study published in Nature.
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Developing Deep Learning Models to Understand the Human Genome
Northwestern Medicine scientists have developed a deep learning algorithm accelerating research around diseases and disorders that occur when the process of DNA transcription goes awry.
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Novel Approaches for Correcting Gene Expression Insufficiency
A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by insufficient protein levels, according to a study published in Nature Communications.
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Investigating the Role of DNA Damage in Cardiac Hypertrophy
A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes which contributes to the development of cardiac hypertrophy according to a Northwestern Medicine study published in Circulation.
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Investigating the Link Between Iron Deficiency and Regulation of Cell Growth
Northwestern Medicine investigators have uncovered new mechanisms by which iron deficiency inhibits cell growth and proliferation in eukaryotic cells, findings that could improve the understanding of cancer growth and the development of targeted cancer therapies.
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Ion Channel Linked to Brain Inflammation Identified
Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.
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Study Discovers Novel Therapeutic Target for Acute Respiratory Distress Syndrome
A new Northwestern Medicine study has discovered a novel therapeutic target and therapeutic agents for older patients with acute respiratory distress syndrome, according to recent findings published in Science Translational Medicine.
