A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes which contributes to the development of cardiac hypertrophy according to a Northwestern Medicine study published in Circulation.
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Browsing: Pharmacology
Northwestern Medicine investigators have uncovered new mechanisms by which iron deficiency inhibits cell growth and proliferation in eukaryotic cells, findings that could improve the understanding of cancer growth and the development of targeted cancer therapies.
Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.
A new Northwestern Medicine study has discovered a novel therapeutic target and therapeutic agents for older patients with acute respiratory distress syndrome, according to recent findings published in Science Translational Medicine.
More cases of children born with abnormal brain development may have genetic explanations than previously thought, according to a recent study published in JAMA Neurology.
Northwestern Medicine scientists have developed a new technique for measuring protein folding stability on an unprecedented scale, according to a new study published in Nature.
Reduced expression of specific calcium channels impaired electrical signaling between neurons and contributed to the onset of behaviors associated with neurodevelopmental disorders and seizure susceptibility in mouse models, according to a Northwestern Medicine study.
Investigators have discovered that a subset of sensory neurons promote osteoarthritis-related joint pain and inflammation, suggesting a new therapeutic target for pain management, according to findings published in Nature Communications.
Northwestern Medicine investigators have discovered novel features of circulating tumor stem cells that can promote chemotherapy evasion and metastasis in triple-negative breast cancer, according to a recent study.
Investigators led by Barbara Stranger, PhD, associate professor of Pharmacology, developed a guide outlining best practices for studying and testing sex-dependent genetic effects in complex traits and diseases, published in the journal Cell.