Tag: Pathology
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Improving Immune Response Against Viral Infections and Disease
Blocking an inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.
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Uncovering Cellular Mechanisms Driving Epidermal Form and Function
A team of Northwestern Medicine investigators have discovered a set of intracellular mechanisms that support the polarized function of the skin’s outermost layer, the epidermis.
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Tackling Inflammation to Improve Heart Attack Recovery
Inhibiting an inflammatory pathway reduced heart attack-induced damage in experimental models, according to a recent Northwestern Medicine study.
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New Understanding of Leukocyte Migration
A recent Northwestern Medicine study has revealed previously unknown details about calcium signaling that can contribute to inflammation.
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Analyzing Plasma Can Classify Brain Tumors
Measuring epigenetic signatures in blood plasma could help classify brain tumors, according to a study published in Nature Medicine.
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Novel Method Maps Virus-Host Protein Interactions
A novel method to map protein-protein interactions between viruses and their hosts more precisely than current methodologies may help improve the design of antiviral drugs and therapeutic strategies.
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Gene Pathway Shows Therapeutic Potential for Treatment of Autoimmune Diseases
A team of Northwestern Medicine investigators identified a specific gene as a key regulator of immune cells called invariant natural killer T cells, which may present therapeutic potential for the treatment of autoimmune diseases.
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New Migration of Brain Tumor Discovered
A previously unknown migration of glioblastoma may explain why current treatments stall out over time, according to a new study.
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Newly Discovered Mechanism May Control Inflammation
A new study has discovered previously unknown details about a mechanism that lets white blood cells travel from blood vessels into tissue, a process key to inflammation.
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Circadian Clock Plays Unexpected Role in Neurodegenerative Diseases
Interruptions in circadian rhythm protected against damage in a model of Huntington’s disease, suggesting an unexpected neuroprotective effect for mild stress to the brain from irregular patterns of sleep.
