Pathology Chair: Evolution of Brain Tumor Classification
Daniel Brat, MD, PhD, has been heavily involved in the process of moving molecular genetic biomarkers for glioma from the bench to the beside.
Browsing: "Pathology"
Uncovering Cellular Mechanisms of Genetic Skin Diseases
Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases.
Study Reveals Potential Therapeutic Target for Genetic Liver Disease
Northwestern Medicine investigators have discovered the molecular mechanisms underlying a rare genetic disorder that increases the risk of severe liver disease, according to a recent study.
Of Balding Mice and Men and Women
A newly discovered cause of balding in aging male mice could reveal a cause of hair loss in men and women as well, reports a study from Northwestern Medicine scientists.
Improving Immune Response Against Viral Infections and Disease
Blocking an inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.
Uncovering Cellular Mechanisms Driving Epidermal Form and Function
A team of Northwestern Medicine investigators have discovered a set of intracellular mechanisms that support the polarized function of the skin’s outermost layer, the epidermis.
Tackling Inflammation to Improve Heart Attack Recovery
Inhibiting an inflammatory pathway reduced heart attack-induced damage in experimental models, according to a recent Northwestern Medicine study.
New Understanding of Leukocyte Migration
A recent Northwestern Medicine study has revealed previously unknown details about calcium signaling that can contribute to inflammation.
Analyzing Plasma Can Classify Brain Tumors
Measuring epigenetic signatures in blood plasma could help classify brain tumors, according to a study published in Nature Medicine.
Novel Method Maps Virus-Host Protein Interactions
A novel method to map protein-protein interactions between viruses and their hosts more precisely than current methodologies may help improve the design of antiviral drugs and therapeutic strategies.