A new Northwestern Medicine study reports that DNA manifested as knot-like folds and third rungs between DNA’s two strands may drive cancer development and an important regulatory enzyme could be associated with the formation of these unusual structures.
Browsing: Genetics
The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.
Northwestern Medicine scientists have discovered a biomarker for one type of autism within cerebrospinal fluid, according to a recent study.
Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons that increases their vulnerability to degeneration.
Long chains of fatty acids in the lysosome are associated with a degenerative form of Gaucher disease, an inherited condition related to Parkinson’s disease.
A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
Human cells use a protein named TBC1D5 to “trap and kill” influenza A viruses inside host cells, but the virus encodes its own protein to disable this defense.