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Home » Genetics » Page 3

Browsing: Genetics

Disease Discoveries
Feb 3, 2022

Genetic Variant of High-risk Childhood Leukemia Revealed

A genetic mutation changing just one base pair of nucleotides greatly increases risk of a lethal subtype of childhood acute lymphoblastic leukemia, according to a recent study.

Scientific Advances
Jan 14, 2022

Genome Editing Made Possible on Cells Lining Blood Vessel Walls

The laboratory of YouYang Zhao, PhD, developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to vascular endothelial cells.

Scientific Advances
Jan 6, 2022

Secondary Structures in DNA are Associated With Cancer

A new Northwestern Medicine study reports that DNA manifested as knot-like folds and third rungs between DNA’s two strands may drive cancer development and an important regulatory enzyme could be associated with the formation of these unusual structures.

Scientific Advances
Dec 20, 2021

Protein ‘Chaperone’ Plays Dual Role in DNA Replication

The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.

Disease Discoveries
Dec 17, 2021

New Autism Biomarker Discovered in Cerebrospinal Fluid

Northwestern Medicine scientists have discovered a biomarker for one type of autism within cerebrospinal fluid, according to a recent study.

Scientific Advances
Dec 16, 2021

Histone Protein Influences Both Neurological Disorder and Cancer

Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.

Scientific Advances
Dec 10, 2021

Uncovering the Degenerative Basis of Parkinson’s Disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons that increases their vulnerability to degeneration.

Disease Discoveries
Dec 7, 2021

Fatty Acid Length Predicts Parkinson’s Disease Risk

Long chains of fatty acids in the lysosome are associated with a degenerative form of Gaucher disease, an inherited condition related to Parkinson’s disease.

Disease Discoveries
Nov 23, 2021

Combination Therapy Reduces Toxic Aggregates in Parkinson’s Disease

A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.

Disease Discoveries
Nov 10, 2021

Study Shows Epigenetic Modification is Central for Tumor Metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

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