Browsing: Genetics

The use of genetic information to inform patient care, from cancer to neurological disorders, has personalized medicine for individual patients like never before. But more is still to come, according to Elizabeth M. McNally, MD, PhD, new director of Northwestern University Feinberg School of Medicine’s Center for Genetic Medicine.

Northwestern Medicine scientists found a genetic biomarker to pinpoint some patients with treatment-resistant schizophrenia, making it possible to give them an effective alternative therapy sooner.

Northwestern Medicine scientists discovered that genetic mutations in the KCNB1 potassium channel gene can result in severe early onset epilepsy.

Nehal Gosalia, ’14 PhD, examined the role of architectural proteins in regulation of expression of the cystic fibrosis gene.

The common cold decreases gene expression in nasal cavity cells, making asthma worse.

Northwestern Medicine scientists have expanded the understanding of how myelodysplastic syndromes develop.

A mathematical model can predict whether a tumor has a gene mutation associated with a favorable prognosis for glioblastoma patients.

Elizabeth McNally, MD, PhD, has been named the Elizabeth J. Ward Chair and director of the Center for Genetic Medicine.

David Kamp, MD, completed his residency and fellowship at Northwestern, where he now studies a range of lung disorders as well as cellular apoptosis, a process of programmed cell death.

Recently published research in Human Molecular Genetics shows that removing too much of the enzyme HDAC3 has a toxic effect on the nervous system. The expression of this enzyme is inhibited by drugs being studied as potential treatment options for cancer and neurodegeneration