Tag: Cell and Developmental Biology
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Study Identifies Two Genes Linked to Microcephaly
Northwestern Medicine scientists have identified pathogenic variants in two genes linked to microcephaly and other neurodevelopmental disorders in children, according to a recent study published in Nature Communications.
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Center for Genetic Medicine Announces New Director for Transgenic and Targeted Mutagenesis Laboratory
Styliani (Stella) Markoulaki, PhD, has been named the new director of the Transgenic and Targeted Mutagenesis Laboratory.
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New Therapeutic Approach Could Prevent Injury to Fragile Transplanted Lungs
Investigators identified a molecular “brake” that can reduce the activation of damaging cells known to cause primary graft dysfunction — a leading culprit in lung transplant failure.
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Study Identifies Distinct Roles for Nuclear Lamin Isoforms
A Northwestern Medicine study has uncovered distinct roles of major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics.
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Cytoskeletal Proteins Interact to Form Intracellular Networks
Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form essential cytoskeletal networks within the cell surface.
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Exploring Flow Transport in Egg Cells
Motor proteins “slingshot” microtubules within developing egg cells of fruit flies, creating a current that transports mRNA to a developing egg.
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New Insights into Cell Polarity
A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.
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Combination Treatment May Prolong HIV Viral Suppression
A novel combination treatment may increase the ability of monoclonal antibodies to control viral infection in patients diagnosed with HIV, according to a Northwestern Medicine study.
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Award Funds International Vascular Malformation Research
An international collaboration for which Luisa Iruela-Arispe, PhD, chair of Cell and Developmental Biology, serves as North American coordinator, has received a five-year, $7 million Transatlantic Networks of Excellence Program award from the Leducq Foundation.
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Investigating Long-Lived Mitochondrial Proteins
Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.
