Investigators at Northwestern Medicine and the Flatiron Institute have characterized how developing cells reorganize their cytoplasm as part of their growth, according to a study published in Nature Physics, a discovery which furthers the field’s understanding of basic cellular processes at the earliest stages of development.
Browsing: Cell and Developmental Biology
Decreased activity of a specific signaling pathway in the brain vessels of aging mice and humans was linked to a decline in vascular function and subsequent neurodegeneration, according to a recent Northwestern Medicine study published in the Journal of Clinical Investigation.
Northwestern Medicine scientists have identified how cytoskeletal proteins contribute to the growth of developing eggs in fruit flies, findings which further the understanding of how egg cells form and differentiate themselves from other cells, according to a study published in the Proceedings of the National Academy of Sciences.
Scientists have created a new synthetic biology approach to follow tumor cells over time, finding meaningful differences in why a cancer cell dies or survives in response to anti-cancer therapies.
A recent Northwestern Medicine study has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of biomarkers and targeted therapies for cancer.
Using zebrafish models, investigators have discovered that MAP4K4 genetic variants cause neurodevelopmental delays and other physical abnormalities, demonstrating a potential therapeutic target for treating the disorder in humans, according to findings published in Science Advances.
Northwestern Medicine scientists have uncovered a mechanism by which exercise activates metabolic benefits in the body, according to a new study published in Cell Metabolism.
Northwestern Medicine scientists have identified pathogenic variants in two genes linked to microcephaly and other neurodevelopmental disorders in children, according to a recent study published in Nature Communications.
Styliani (Stella) Markoulaki, PhD, has been named the new director of the Transgenic and Targeted Mutagenesis Laboratory.
Investigators identified a molecular “brake” that can reduce the activation of damaging cells known to cause primary graft dysfunction — a leading culprit in lung transplant failure.