Investigators identified a molecular “brake” that can reduce the activation of damaging cells known to cause primary graft dysfunction — a leading culprit in lung transplant failure.
A Northwestern Medicine study has uncovered distinct roles of major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics.
Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form essential cytoskeletal networks within the cell surface.
Motor proteins “slingshot” microtubules within developing egg cells of fruit flies, creating a current that transports mRNA to a developing egg.
A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.
A novel combination treatment may increase the ability of monoclonal antibodies to control viral infection in patients diagnosed with HIV, according to a Northwestern Medicine study.
An international collaboration for which Luisa Iruela-Arispe, PhD, chair of Cell and Developmental Biology, serves as North American coordinator, has received a five-year, $7 million Transatlantic Networks of Excellence Program award from the Leducq Foundation.
Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.
Migrating cells use stiffened microtubules to push through tissue barriers, seeking out weak points in tissue, according to a recent study.
A study led by Northwestern Medicine investigators has identified the molecular mechanisms within protein complexes that promote cell-to-cell adhesion and communication.