Tag: Cancer
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Examining Use of Small-molecule Inhibitors in Preserving Fertility
Scientists have demonstrated that a small-molecule inhibitor can preserve fertility in mice, when administered as a co-treatment with conventional chemotherapy.
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Insights Into the Essential Building Blocks of the Nucleus
A new study defined the architecture of nuclear lamins, the fibrous proteins in a cell’s nucleus, providing further insights into their role in cell structure.
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Using Stem Cells to Predict Toxicity of Chemotherapy Drugs
A Northwestern Medicine study has established a new safety index for a common group of chemotherapy drugs, by using a stem cell model to screen such therapies for cardiotoxicity.
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Molecule Stops Fatal Pediatric Brain Tumor
In research published in Nature Medicine, Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor for which there is no current treatment.
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Evaluating A Novel Chemo-free Combination Therapy for Lymphocytic Leukemia
A phase 1 clinical trial of venetoclax and rituximab combination therapy was shown to be an effective chemo-free treatment option for patients with difficult-to-treat chronic lymphocytic leukemia.
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Novel Biomarker Predicts Treatment Response in Chronic Leukemia
A newly identified biomarker may predict treatment response in patients with chronic myelogenous leukemia, according to a Northwestern Medicine study.
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Evaluating a Therapy for Rare Midgut Tumors
In recent Northwestern Medicine clinical trials, an experimental drug improved survival rates for patients with advanced midgut neuroendocrine tumors compared to a standard therapy.
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Insights Into Key Molecular Process Underlying Many Cancers
A paper published in Molecular Cell provides new insight into a protein complex called COMPASS and its function during histone methylation, a key modification that regulates gene expression.
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Medical Student Investigates Cervical Cancer Surgery Survival
A surgical procedure called a pelvic exenteration may be curative for more than half of women with a form of advanced cervical cancer who have failed other treatments.
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Insights Into Enzyme Targets Could Lead to New Cancer Therapies
Northwestern Medicine scientists have identified the unique targets of two enzymes that activate ubiquitination, a key modification of proteins that controls a variety of cellular processes.
