Northwestern Medicine scientists have discovered a new potential drug therapy for pediatric brainstem glioma by targeting a genetic mutation found in patients with the rare, incurable cancer.
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Inhibiting a ubiquitin ligase stops tumor growth during hypoxia, a common characteristic of lung and brain cancers.
Leonidas Platanias, MD, PhD, has been appointed director of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, a position he has served in interim since January.
Northwestern Medicine scientists have found a new method to measure how patients with breast cancer liver metastasis respond to treatment.
Mary J.C. Hendrix, PhD, revealed a variance in signaling pathways in embryonic stem cells and metastatic melanoma cells that may impact new therapeutic strategies in cancer.
Northwestern Medicine scientists identified a previously unknown signaling pathway that enhances tumor growth in glioblastomas and head and neck cancers. The proteins in the pathway could be targeted in the treatment of human cancers.
Young adult cancer survivors reported poorer physical and emotional health but better social health in a study by Northwestern Medicine scientists.
A mathematical model can predict whether a tumor has a gene mutation associated with a favorable prognosis for glioblastoma patients.
Prostate cancer cells producing too much PIM1 are particularly sensitive to the inhibition of a protein called polo-like kinase (PLK1).
Metformin, a drug used to lower insulin levels in diabetics, has been shown to halt tumor progression by cutting cancer cells’ energy supply.