Tag: Cancer
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Novel Drug Improves Survival in Advanced Prostate Cancer
A novel drug called enzalutamide may extend overall survival for men with nonmetastatic, castration-resistant prostate cancer, according to findings from clinical trial published in The New England Journal of Medicine.
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Chimeric Toxin Slows Cancer Growth
A novel compound using diphtheria toxin to attack a signaling pathway implicated in as many as 50 percent of cancers slowed tumor growth, according to a recent study.
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Exploring Protein Vital for Bone Marrow Transplants
A protein called mDia2 is vital for proper bone marrow transplantation, according to a new study.
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Strategies for Evaluating Breast Cancer with Machine Learning
Machine-learning technology could help pathologists more accurately assess how a patient’s immune system is responding to breast cancer, according to a recent series of reports authored in part by Feinberg faculty.
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New Genetic Regulators Could Improve Cancer Immunotherapy
A genetic screen has revealed previously unknown regulators of Foxp3, a transcription factor that, when deactivated, may improve patient response to aggressive cancers.
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New Mechanism for Oncogenic Gene Splicing
Northwestern Medicine scientists have discovered an alternate mechanism for aberrant gene splicing that contributes to T-cell lymphoblastic leukemia, according to a recent study.
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Chemotherapy for Early Stage Breast Cancer Associated with Greater Cognitive Impairment
In women with early-stage breast cancer, Northwestern Medicine investigators found chemoendocrine therapy was associated with greater cognitive impairment at three and six months compared to endocrine therapy alone.
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Cancer Cells Hijack Nucleotide Metabolism to Boost Cell Proliferation
Mutations in the genes RAS and RAF allow cancer cells to create their own nucleotides, fueling cancer growth, according to a recent study published in Molecular Cell.
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Origin of Cancer Cells Influences Skin Cancer Prognosis
A new Northwestern Medicine study found important differences in rare skin lymphomas stemming from their specific cell of origin and clinical presentations, according to findings published in Nature Communications.
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New Function for Transcriptional Regulator Discovered
A new Northwestern Medicine study discovered a new and unexpected function for the transcriptional regulator MLL2/COMPASS.
