Tag: Biochemistry and Molecular Genetics
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Streamlining Chemical-Genetic Screening
Northwestern Medicine scientists have developed a new high-throughput sequencing tool to test how drugs interact with genetically modified cells.
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Discovering New Mechanisms in Epigenetics
A series of recent discoveries by Northwestern Medicine scientists point to a more nuanced understanding of how epigenetic regulators function.
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Mitochondria-Targeted Antioxidants Inhibit Tumor Growth
Northwestern Medicine investigators have discovered that inserting dietary antioxidants into the mitochondria of cancer cells may inhibit overall tumor growth.
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Scientists Unravel Zebrafish Epigenome
A new Northwestern Medicine study has identified tissue-specific epigenetic regulators in zebrafish, filling in a longtime gap in the understanding of the organism’s genome.
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Unusual Epigenetic Regulator Could Impact Cancer
A newly discovered function of an epigenetic regulator could be a key to new cancer treatments, according to a new study published in Genes and Development.
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New Details on T-Cell Methylation
The DNA methylation landscape of regulatory T-cells is more complex than previously understood, according to a new Northwestern Medicine study.
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New Drug Target for Treatment-Resistant Prostate Cancer
Inhibiting an epigenetic regulator called DOT1L could be a key to slowing treatment-resistant prostate cancer, according to a recent Northwestern Medicine study.
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Understanding Mitochondrial Dysfunction’s Impact on Neurological Diseases
A recent Northwestern Medicine study may improve the understanding of mitochondrial dysfunction and its impact on the development of neurological diseases.
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New Machine-learning Method to Identify Chromatin Loops
A machine-learning program called Peakachu can reveal previously unknown chromatin loops, according to a Northwestern Medicine study published in Nature Communications.
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Mitochondrial Metabolism Shows Promise as Target for Cancer Therapy
Northwestern Medicine investigators have discovered that the growth of cancerous tumors requires the activation of a specific biochemical process within the mitochondria of tumor cells, showing potential as a new target for cancer therapy.
