Inhibiting SAM Biosynthesis to Slow Tumor Growth
Inhibiting production of a key material produced by the mTOR pathway could slow tumor growth, according to a recent Northwestern Medicine study.
Browsing: "Biochemistry-and-molecular-genetics"
Next-Gen Sequencing
Northwestern’s investment in next-generation sequencing is leading to unprecedented avenues of discovery.
Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
Uncovering How Protein Complexes Impact Gene Expression
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
Streamlining Chemical-Genetic Screening
Northwestern Medicine scientists have developed a new high-throughput sequencing tool to test how drugs interact with genetically modified cells.
Discovering New Mechanisms in Epigenetics
A series of recent discoveries by Northwestern Medicine scientists point to a more nuanced understanding of how epigenetic regulators function.
Mitochondria-Targeted Antioxidants Inhibit Tumor Growth
Northwestern Medicine investigators have discovered that inserting dietary antioxidants into the mitochondria of cancer cells may inhibit overall tumor growth.
Scientists Unravel Zebrafish Epigenome
A new Northwestern Medicine study has identified tissue-specific epigenetic regulators in zebrafish, filling in a longtime gap in the understanding of the organism’s genome.
Unusual Epigenetic Regulator Could Impact Cancer
A newly discovered function of an epigenetic regulator could be a key to new cancer treatments, according to a new study published in Genes and Development.
New Details on T-Cell Methylation
The DNA methylation landscape of regulatory T-cells is more complex than previously understood, according to a new Northwestern Medicine study.