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Bethany Ekesa, Associate Director of SPARC, Honored with Jean E. Shedd University Citizenship Award
Bethany Ekesa, associate director of Feinberg’s Sponsored Project and Research Catalysts (SPARC) team, was selected as the recipient of the 2023 Jean E. Shedd University Citizenship Award.
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Combination Immunotherapy Shows No Additional Benefit for Most Advanced Cancers
A combination immunotherapy treatment of nivolumab plus ipilimumab was associated with no improvement in survival for advanced cancers other than melanoma, when compared to nivolumab alone, according to a recent Northwestern Medicine meta-analysis published in JAMA Oncology.
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Novel Intercellular Signaling Mechanisms Promote Melanoma Growth
Investigators have discovered novel intercellular “crosstalk” between epidermal keratinocytes and melanoma cells that promotes cancer growth and metastasis, which could also serve as biomarkers for early cancer detection, according to a recent Northwestern Medicine study.
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Protein Controls Lymphoma Cell Metabolism, Promotes Cancer Growth
Northwestern Medicine investigators have discovered how the PD-1 protein controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas, according to a study published in Nature Cancer.
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Feinberg Receives Record-Breaking Research Funding in 2023
Feinberg principal investigators secured $706 million in research funding and awards during the 2022-23 fiscal year, which is a nearly nine percent increase over the previous year, and the largest amount in the school’s history.
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Study Identifies Novel Cellular Mechanisms Promoting Growth of Uterine Fibroids
Northwestern Medicine investigators have discovered a novel molecular pathway that promotes tumor growth in uterine fibroids, findings that could inform the development of new targeted therapies, according to a recent study.
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Newly Discovered Trigger of Parkinson’s Upends Common Beliefs
A new study suggests that a dysfunction in neurons’ synapses leads to deficits in dopamine and precedes the neurodegeneration previously thought to cause Parkinson’s disease.
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Research Day 2023 Celebrates Scientific Discoveries and Collaboration
Feinberg investigators, students, trainees and faculty celebrated discovery and presented scientific research at Feinberg’s 17th annual Lewis Landsberg Research Day on Sept. 14.
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Ion Channel Linked to Brain Inflammation Identified
Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.
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Physicians and Medical Students Delay Childbearing, Family Building Due to Medical Training
More than 60 percent of physicians and medical students reporting delaying having children and building a family due to medical training, with half also having regretted doing so, according to recent survey findings published in JAMA Internal Medicine.
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Your Body’s Own Cannabinoid Molecules Calm You During Stress
A new Northwestern Medicine study has discovered that a key emotional brain center, the amygdala, releases endogenous cannabinoid molecules under stress, and these molecules dampen the incoming stress alarm from the hippocampus, a memory and emotion center in the brain.
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Engineered Probiotic Can ‘Sense’ Inflammatory Bowel Disease
Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
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First Device to Monitor Transplanted Organs, Detect Early Signs of Rejection
Northwestern University investigators have developed the first electronic device for continuously monitoring the health of transplanted organs in real time.
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New Genetic Variants Associated with Resting Heart Rate and Cardiovascular Disease Risk
Investigators have identified more than 60 previously unknown genetic variants associated with resting heart rate that may also contribute to increased risk of cardiovascular disease, according to findings published in Nature Communications.
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Gene Linked to HIV Viral Load in People of African Ancestry
Naturally occurring variations near the human gene CHD1L may be linked to lower HIV-1 viral load in people of African ancestry, according to a new international, multicenter study published in Nature.
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Cella Named 2023 Tripartite Prize Recipient
David Cella, PhD, professor of Medical Social Sciences, has been named the winner of the 2023 Tripartite Legacy Faculty Prize in Translational Science and Education.
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Understanding Mechanisms Underlying Skin Development
Northwestern Medicine scientists have revealed how a gene considered essential for histone modification regulates skin development, according to a recent study published in Nature Communications.
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Evaluating Implementation Strategies for Tobacco Use Treatment in Cancer Care
Electronic health record-based messages delivered solely to clinicians increased referral to tobacco use treatment for cancer patients who smoke, according to a recent study published in the Journal of Clinical Oncology.
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Uncovering the Molecular Underpinnings of Inflammation
Northwestern Medicine investigators have identified new molecular details regarding how white blood cells move across the walls of microvessels during inflammation, revealing new potential molecular targets for treating the condition, according to a new study published in the journal Immunity.
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Student Research Honors Late Mentor and Discovers New Blood Cancer Treatment
Brian Lee, a second-year student in the Medical Scientist Training Program (MSTP), was the lead author of a study that found that a new combination therapy regimen improved survival in patients with B-cell lymphoma by 30 percent.
