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Evaluating Perioperative Chemotherapy for Pancreatic Cancer
Perioperative chemotherapy treatment did not improve overall survival for patients with resectable pancreatic cancer, according to a recent Northwestern Medicine clinical trial.
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Celebrating 75 Years of Partnership with the VA
A model forged at Northwestern, academic affiliations with Veteran’s hospitals changed American medicine — providing care for veterans, training for future physicians and advancing scientific discovery.
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Blocking Cell Division in Glioblastoma
Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
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Northwestern Investigators Explore COVID-19 Treatments
Working with large, multicenter teams, Northwestern clinician-scientists have examined treatments for blood clotting in critically ill patients with COVID-19, and explored therapies that could reduce disease progression and hospitalization.
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Tackling Inflammation to Improve Heart Attack Recovery
Inhibiting an inflammatory pathway reduced heart attack-induced damage in experimental models, according to a recent Northwestern Medicine study.
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Physical Therapy Student Helps Save a Life
Alyssa Martinez, a second-year student in the Doctor of Physical Therapy (DPT) program, recently put her newly acquired medical skills to use to help save a man’s life.
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Untangling Cellular Changes in Pediatric Epilepsy
For the first time, Northwestern Medicine scientists have characterized how a genetic mutation associated with pediatric epilepsy affects neuron activity.
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Inhibiting Protein Degradation May Prevent Cocaine-Induced Reward Behaviors
Northwestern Medicine investigators have discovered that inhibiting a specific autophagy protein found in dopaminergic neurons may prevent reward-related behaviors induced by cocaine misuse.
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Identifying Therapeutic Targets for B-cell Acute Lymphoblastic Leukemia
Northwestern Medicine investigators have identified a protein kinase called DYRK1A and its downstream substrates as potential therapeutic targets for treating pediatric patients with B-cell acute lymphoblastic leukemia.
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Antibody Drug Improves Survival for Aggressive Breast Cancer
A new antibody drug demonstrated similar efficacy to currently available therapies to treat advanced ERBB2-positive breast cancer, according to a recent clinical trial.
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Mother’s Heart Health in Pregnancy Impacts Child’s Heart Health in Adolescence
A mother’s heart health while she is pregnant may have a significant impact on her child’s cardiovascular health in early adolescence, according to a new study from Northwestern and Lurie Children’s Hospital.
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Second-year Medical Student Reflects on Music, Research and Volunteer Opportunities
Second-year medical student and musician Mallika Patel reflects on collaborative research efforts with Feinberg faculty and her experience volunteering for the COVID-19 Med Supply Drive’s Illinois chapter.
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Novel Injectable Therapy Shows Promise in Treating Crohn’s Disease
A team of Northwestern investigators has demonstrated that injection of anti-inflammatory peptide amphiphiles into intestinal lesions can reduce inflammation in an animal model of Crohn’s disease.
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Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
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Uncovering How Protein Complexes Impact Gene Expression
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
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New Anti-Obesity Medication Almost Twice as Effective as Most Currently Approved Weight-Loss Drugs
A new anti-obesity medication is almost twice as effective at helping individuals lose weight than current weight-loss drugs, according to a Northwestern Medicine study.
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Why Black Men’s Prostate Cancer May be More Responsive to Immunotherapy
A new Northwestern Medicine study has discovered why Black men die more often of prostate cancer yet also have greater survival benefits from immunotherapy treatments.
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Plotting the Neural Circuitry of Appetite Suppression
Northwestern Medicine scientists have uncovered a neural circuit that drives fear-induced suppression of feeding, according to a study published in Neuron.
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Multi-faceted Therapeutic Target for Metabolic Syndrome Discovered
Northwestern Medicine investigators have discovered a potential multi-faceted therapeutic target for preventing and treating the metabolic syndrome, according to a recent study.
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Cardio-Kidney Trials Present Obstacles
A new class of drugs shows benefit for both cardiovascular and kidney conditions, but scientists should be cautious in designing trials that include both cardiovascular and kidney outcomes in the same analysis, according to a Northwestern Medicine review article.
