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Drug May Benefit Patients with Heart Failure
Dapagliflozin, a drug commonly used to treat type 2 diabetes, improved heart failure-related symptoms and physical limitations in patients with heart failure with preserved ejection fraction.
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Identifying Cancer Biomarkers for Immunotherapy Response
Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs.
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Combination Therapy Reduces Toxic Aggregates in Parkinson’s Disease
A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
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NUPOC Students Create Teddy Bear Braces for Lurie Children’s Patients
On November 5, students in the Master of Prosthetics & Orthotics (MPO) program through Northwestern’s Prosthetics-Orthotics Center constructed more than 50 braces for teddy bears gifted to pediatric patients at Ann & Robert H. Lurie Children’s Hospital.
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Respiratory Virus Reprograms Airway Epithelial Cells
Respiratory syncytial virus infection during infancy results in metabolic reprogramming in epithelial cells lining the airway, according to a recent study.
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How Herpes Checks Into the Nervous System for Life
A new Northwestern Medicine study has uncovered herpes’ sneaky strategy for infecting the nervous system, opening a path to long-needed vaccine development for the virus.
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Northwestern Receives Grant to Support Equity in Biomedicine
Northwestern University Feinberg School of Medicine has been awarded a $550,000 grant to support the retention of early-career clinician investigators experiencing family caregiving challenges due to the COVID-19 pandemic.
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Drug May Improve Cardiac Function in Hypertrophic Cardiomyopathy
Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to a recent clinical trial.
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Neurobiologists Identify a New Gene Important for Healthy Daily Rhythms
A recent study identified a gene that is critical for daily behavioral rhythms, involved in a molecular pathway by which the core circadian clock controls daily sleep-wake cycles.
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Inge Joins Lurie Children’s Hospital as Surgeon-in-Chief
Ann & Robert H. Lurie Children’s Hospital of Chicago has recruited an internationally recognized surgeon-scientist, Thomas H. Inge, MD, PhD, as the hospital’s next surgeon-in-chief.
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New Insights into Cell Polarity
A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.
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‘Dancing Molecules’ Successfully Repair Severe Spinal Cord Injuries
A new injectable therapy harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries, allowing animal subjects to regain the ability to walk.
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Students Practice Ophthalmology Surgical Techniques
The student-led Ophthalmology Interest Group recently held a suturing workshop, offering Feinberg students the opportunity to practice surgical techniques on mock organs.
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Study Shows Epigenetic Modification is Central for Tumor Metastasis
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
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Second-year Students Present AOSC Projects
Second-year medical students presented Area of Scholarly Concentration (AOSC) research projects during a virtual session held November 5.
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Northwestern Medicine Investigators Receive $14 Million Grant to Study Viral Pneumonia
An interdisciplinary team of Northwestern Medicine investigators led by Karen Ridge, PhD, has been awarded a $14 million grant from the National Heart, Lung, and Blood Institute to study the mechanisms that promote lung tissue repair in patients with severe viral pneumonia.
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New Insights into the Mechanism of ALS
The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
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A New Way to Improve Skilled Movements Via Sleep
The ability to learn novel physical movements, similar to those taught in rehabilitation for people with stroke, can be improved by reactivating specific memories of the new task during sleep, according to a new study.
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Les Turner ALS Symposium Celebrates Advances in Research and Patient Care
Northwestern scientists and clinicians demonstrated their continued commitment to advancing knowledge and therapies for amyotrophic lateral sclerosis during the 11th annual Les Turner Symposium on ALS.
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Gene Therapy Boosts Parkinson’s Disease Drug Benefits
A new Northwestern Medicine study published in Nature explains why dopamine neurons are lost in Parkinson’s disease, and demonstrated that a gene therapy targeting the brain’s substantia nigra can substantially boost the benefits of levodopa, an important medication for treating the disease.
