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Study Investigates Crosstalk Between Mitochondria and Lysosomes
Northwestern Medicine investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, findings that have implications for many diseases.
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Medical School Receives Largest Research Funding in 2022
Feinberg principal investigators secured $650 million in research funding and awards during the 2021-22 fiscal year, which is a 6.5 percent increase over the previous year, and the largest amount in the school’s history.
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Lurie Cancer Center Uses Data Collection to Address LGBTQ Health Disparities
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University will begin scaling up its collection and use of data related to patient sex assigned at birth, gender identity, and sexual orientation with funding from the National Cancer Institute.
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Why Late-Night Eating Leads to Weight Gain, Diabetes
A new study has shown that energy release may be the molecular mechanism through which our internal clocks control energy balance, findings with implications from dieting to sleep loss.
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Evaluating Treatment Options for Peripheral Artery Disease
Telmisartan, an angiotensin receptor blocker drug, did not improve walking performance in patients with lower extremity peripheral artery disease, according to a recent clinical trial published in JAMA.
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Study Uncovers Role of Mitochondrial Energy Production in Dopaminergic Neurons
Northwestern Medicine investigators have discovered that dopaminergic neurons in the substantia nigra utilize a specific ion channel to control energy production and meet bioenergetic need, according to a recent study.
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Kimberly Querrey, Louis Simpson Trust Give $100 Million to Feinberg
Northwestern University Trustee Kimberly K. Querrey and the Louis Simpson Trust have made a new $100 million gift to the Feinberg School of Medicine to significantly expand the university’s biomedical research enterprise.
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Preventing Maternal Mortality and Morbidity
The Supreme Court ruling in Dobbs v. Jackson Women’s Health Organization has created confusion for many women seeking medical care when pregnant. Nevertheless, Feinberg investigators continue to pursue research that identifies important factors that impact maternal health.
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Improving the Care of Opioid Use Disorder and Pain
Sara Becker, PhD, director of IPHAM’s Center for Dissemination and Implementation Science, and C Hendricks Brown, PhD, professor of Psychiatry and of Behavioral Sciences, are principal investigators on a new $15.8 million center grant funded by the National Institute on Drug Abuse.
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Krainc Elected to the National Academy of Medicine
Dimitri Krainc, MD, PhD, chair and Aaron Montgomery Ward Professor of Neurology, has been elected to the National Academy of Medicine.
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Newly Identified Protein Drives Breast Cancer Stemness and Metastasis
Using machine learning, Northwestern scientists have demonstrated that the protein membrane CD81 interacts with CD44 in promoting tumor cell cluster formation and lung metastasis of triple negative breast cancer.
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Novel Monoclonal Antibody Therapy for SARS-CoV-2
Targeting internal proteins instead of spike proteins may be a promising strategy for monoclonal antibody therapy to combat SARS-CoV-2, the virus that causes COVID-19.
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Center for Genetic Medicine Announces New Director for Transgenic and Targeted Mutagenesis Laboratory
Styliani (Stella) Markoulaki, PhD, has been named the new director of the Transgenic and Targeted Mutagenesis Laboratory.
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Asian Americans’ Obesity Prevalence is not One-Size-Fits-All
There is significant variation in the prevalence of obesity among subgroups of Asian American adults, according to a recent Northwestern Medicine study.
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Novel Treatment Effective for Bladder Cancer, Study Shows in Mice
An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, according to a new study.
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Investigating the Role of Fatty Acids in Cancer Cell Survival
Northwestern Medicine investigators have discovered that a particular enzyme is essential for regulating cancer cell survival and metastasis under cellular stress, according to a recent study.
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Northwestern Investigates COVID-19: Sentinel Surveillance, ‘Long COVID’ in Children
Northwestern Medicine investigators continue to investigate the impact of the COVID-19 pandemic, from evaluating repurposed drugs in preventing severe disease to using sentinel surveillance to monitor SARS-CoV-2 transmission rates and studying the prevalence of “long COVID” in pediatric patients.
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Study Identifies Mechanisms Promoting Bacterial Survival
Northwestern Medicine investigators have uncovered novel regulatory mechanisms that promote bacterial survival, according to findings published in PNAS.
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Targeting Ion Channels to Manage Osteoarthritis Pain
Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy for managing osteoarthritis pain, according to a Northwestern Medicine study.
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Widespread Bias, Discrimination Directed Toward People With Disabilities Who Seek Healthcare
A new study shows physicians may be choosing to deny care to people with disabilities, and some use discretionary excuses to strategically discharge them from their practice.