Category: Disease Discoveries
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Eyes May Reveal Early Alzheimer’s Disease
Reduced blood capillaries in the back of the eye may be a new, noninvasive way to diagnose early cognitive impairment, a precursor to Alzheimer’s disease.
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Circadian Clock Plays Unexpected Role in Neurodegenerative Diseases
Interruptions in circadian rhythm protected against damage in a model of Huntington’s disease, suggesting an unexpected neuroprotective effect for mild stress to the brain from irregular patterns of sleep.
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Scientists Identify Therapeutic Target in Diabetic Kidney Disease
In a study published in the Journal of Experimental Medicine, Northwestern Medicine scientists identified a new therapeutic target that may help protect kidney function in patients with diabetes.
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Tumor Mutations Predict Response to Immunotherapy
A recent Northwestern Medicine study found that patients with glioblastoma responded better or worse to immunotherapy depending on the presence of certain mutations in their tumors.
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Alzheimer’s Treatment Holds Promise for Primary Progressive Aphasia Patients
Northwestern Medicine scientists have discovered that an existing therapy used to treat Alzheimer’s disease might also work on patients with Primary Progressive Aphasia, a type of dementia that destroys language and currently has no treatment.
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Nanoparticle Peptides Could Fight Neurodegenerative Disease
According to a recent study, a novel nanoparticle-based drug repaired neurons and improved microvasculature in a mouse model of spinocerebellar ataxia 1, a degenerative disease that affects the cerebellum.
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New Group of Neurons Implicated in Parkinson’s Disease
Abnormal activation of a small population of neurons may contribute to motor learning and motor function deficits in patients with Parkinson’s disease, according to a recent study.
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Therapeutic Toxins
Northwestern investigators are exploring the potential of bacterial toxins to be turned into therapeutic agents to effectively ward off disease.
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Solving Resistance to Emerging Cancer Immunotherapy
According to a recent study, Northwestern scientists have pinpointed how an ectoenzyme called CD73 undermines the effectiveness of an emerging cancer therapy.
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New Role for Dopamine in Deadly Brain Cancer
A Northwestern Medicine study has demonstrated the role of dopamine in the progression of glioblastoma and suggests that targeting the neurotransmitter may slow cancer growth.
