Category: Disease Discoveries
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Leading Translational Gastroenterology Research
Northwestern Memorial Hospital was recently ranked seventh in the country for Gastroenterology & Gastrointestinal (GI) surgery by US News and World Report. This article was originally published in August 2022 Breakthroughs.
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Inflammatory Signaling Linked to Leukemia Progression
An inflammatory signaling protein called interleukin-6 has been linked to the progression of acute myeloid leukemia, representing a potential target for future treatments of the disease.
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New Therapeutic Approach Could Prevent Injury to Fragile Transplanted Lungs
Investigators identified a molecular “brake” that can reduce the activation of damaging cells known to cause primary graft dysfunction — a leading culprit in lung transplant failure.
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Tracking COVID-19 from the Amazon to Chicago
Northwestern Medicine scientists are expanding the global network of COVID-19 sequencing in regions where there is limited viral genetic information reporting.
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Epigenetic ‘Priming’ Boosts Cancer Immunotherapy
An epigenetic inhibitor increased immune system activity in patients with ovarian cancer.
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Light During Sleep in Older Adults Linked to Obesity, Diabetes, High Blood Pressure
Exposure to light during sleep was associated with obesity, diabetes and high blood pressure in older adults, according to a recent study.
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Brain Lesion Location Influences Addiction Behaviors
Damage to particular regions of the brain may influence addiction behaviors, providing insight into potential therapeutic targets for substance use disorders.
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Targeting Bicarbonate in Cancer
Bicarbonate ions are required for cell growth in some cancers, according to a Northwestern Medicine study.
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Anti-seizure Medication has a New Target
Designed to target AMPAR receptors in the brain, the medication — called perampanel — also modulates kainate receptors.
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Epigenetic Biomarkers Predict CVD Risk
A new study provides evidence that blood epigenetic biomarkers contain “snapshots” of past cardiovascular health exposures and behavior at the molecular level.
