Browsing: Clinical Breakthroughs

Northwestern Medicine investigators have shown that inhibiting a mutated gene can reduce seizure activity in adult-type diffuse gliomas, according to a study published in the Journal of Clinical Investigation.

CT scans are better at predicting a middle-aged person’s risk for a heart disease, such as a heart attack, than genetics, reports a new Northwestern Medicine study published in JAMA.

Salt substitutes may be effective in lowering blood pressure and reducing cardiovascular events in residents of elderly care facilities, according to a recent multi-center study published in Nature Medicine.

From 1999 through 2020, Black Americans experienced more than 1.6 million excess deaths and more than 80 million excess years of life lost compared to white Americans, according to a recent study published in JAMA.

A team led by Northwestern Medicine investigators have discovered novel cellular mechanisms that lead to chemotherapy resistance in recurrent glioblastoma, according to findings published in Science Advances.

An informational communications tool provided to patients with dilated cardiomyopathy helped increase cardiovascular screenings in their first-degree relatives who have a higher risk of developing the genetic disease, according to findings published in Circulation.

A novel protein developed by Northwestern Medicine investigators improved survival and prevented brain infection in mice infected with SARS-CoV-2 when administered intranasally, according to a recent study.

Patients with endometrial cancer who received the immunotherapy drug pembrolizumab in addition to chemotherapy had longer progression-free survival compared to chemotherapy alone, according to a recent clinical trial published in the New England Journal of Medicine.

A Northwestern Medicine study used a novel ultrasound device to temporarily open the blood-brain barrier to deliver chemotherapy to treat glioblastoma.

Northwestern Medicine scientists have developed a biomarker signature test to predict which tumors will respond to immunotherapy.