Category: Clinical Breakthroughs
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Experimental Stroke Drug Slows Bleeding but Doesn’t Improve Recovery
A global clinical trial has found that recombinant factor VIIa, a drug designed to rapidly slow bleeding in the brain after a hemorrhagic stroke, does not improve long‑term recovery for patients, according to a study published in The Lancet
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Advancing Preventive Care and Cardiovascular Risk Prediction Through Online Tools
Recently named to the Time100 Health 2026 list, Sadiya Khan, MD, is establishing herself as a leader in preventive cardiology and calling for younger people to think about their heart health earlier in life.
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Common Anti-Seizure Drug Prevents Alzheimer’s Plaques from Forming
Northwestern University scientists have pinpointed when and where toxic proteins accumulate within the brains of Alzheimer’s patients — and discovered a decades-old Food and Drug Administration (FDA)-approved drug that can stop the accumulation process before it even begins, according to a recent study published in Science Translational Medicine.
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Combination Treatment May Slow Disease Progression in Advanced Sarcoma
An oral combination treatment may prevent disease progression in patients with advanced leiomyosarcoma, one of the most common subtypes of soft tissue sarcoma, according to a recent study published in The Lancet Oncology.
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Study Finds Widespread Screening for Rare Cholesterol Disorder Not Cost-Effective
Screening all young people for a genetic form of dangerously high cholesterol could prevent heart attacks and strokes later in life, but would not be cost-effective under the current healthcare system, according to a new modelling study published in JAMA.
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First-Of-Its-Kind Probe Monitors Fetal Health in Utero During Surgery
Northwestern University scientists have developed the first device that can continuously track a fetus’s vital signs while still in the uterus — a feat that previously has not been possible.
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Identifying Mechanisms Supporting Nanoparticle Therapy for Autoimmune Diseases
Northwestern Medicine scientists in the laboratory of Stephen Miller, PhD, have identified the cellular and molecular mechanisms required for the antigen-specific tolerance inducing abilities of a novel nanoparticle therapy for treating autoimmune diseases, according to a recent study published in Science Advances.
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Common Procedure Does Not Prevent Recurrent Pancreatitis, Trial Finds
A multicenter clinical trial published in JAMA has found that a long-used endoscopic procedure does not prevent recurrent pancreatitis in adults with an anatomic anomaly, challenging decades of conventional wisdom.
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Non-invasive Approach Predicts Chemotherapy Response in Glioblastoma
Northwestern Medicine scientists have developed a new non-invasive approach that could help better determine which patients with glioblastoma are responding favorably to chemotherapy treatment and inform future treatment plans, according to a recent study published in Nature Communications.
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Evaluating Treatment of Heart Defects in Preterm Infants
Early pharmacologic treatment of a common congenital heart defect did not improve survival outcomes compared to expectant management in preterm infants, according to a recent clinical trial published in JAMA.
