Author: mrr5831
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Novel Cell ‘Switches’ Promote Lung Cancer Growth, Treatment Resistance
Northwestern Medicine investigators have revealed new insights into how cell type switches facilitate tumor growth and treatment resistance in small cell lung cancer, according to findings published in Science Advances.
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Exploring Genetic Regulation of Immunoglobulin A
Increased levels of the antibody immunoglobulin A (IgA) are correlated with the manifestation of several diseases and African ancestry, according to findings published in Nature Communications.
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Investigating Quality of Life in Large B-cell Lymphoma
Patient-reported outcomes in relapsed or refractory large B-cell lymphoma revealed that receiving CAR T-cell immunotherapy was associated with higher quality of life, according to a recent study.
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Northwestern Investigators Develop New Therapy for Autism Subtype
A team of Northwestern investigators led by Peter Penzes, PhD, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder.
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Study Uncovers Potential Therapeutic Approach for Advanced Prostate Cancer
A Northwestern Medicine study has discovered that elevated PALI1 in advanced prostate tumors mediates crosstalk between two primary epigenetic silencing mechanisms, suggesting that dual epigenetic inhibition may be an effective therapeutic strategy.
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Personalized T-cell Therapy Improves Immune Response Against Cancer
Investigators have developed a novel personalized T-cell therapy approach that may identify specific targets unique to a patient’s cancer cells more effectively than current treatments, according to findings published in Nature.
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Investigating Disparities in Machine Learning Algorithms
Integrating social determinants of health helped mitigate bias when predicting long-term outcomes for heart failure patients, according to a Northwestern Medicine study.
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Novel Mechanisms Regulate Inflammatory Skin Diseases
Northwestern Medicine investigators have identified novel intracellular mechanisms that could serve as future therapeutic targets for inflammatory skin diseases.
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Study Identifies Novel Epigenetic Changes in Pediatric Brain Cancer
Investigators have identified previously unknown sets of epigenetic changes in pediatric brain tumors, which could serve as novel therapeutic targets and provide alternative treatment options.
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New Center for Collaborative AI in Healthcare
The Institute for Artificial Intelligence in Medicine (I.AIM) has established the Center for Collaborative AI in Healthcare, with the mission of advancing artificial intelligence science, engineering and translation throughout healthcare specialties and create a positive impact on precision medicine.
