A new study defined the architecture of nuclear lamins, the fibrous proteins in a cell’s nucleus, providing further insights into their role in cell structure.
Browsing: Scientific Advances
Revolutionary nanomaterials developed at Northwestern could make it possible to repair tissues and organs spanning from bone and cartilage to muscle and brain tissues.
Northwestern Medicine scientists identified the process by which a calcium channel called the CRAC channel opens and closes, and how mutations in the channel structures that control its opening cause disease.
A paper published in Molecular Cell provides new insight into a protein complex called COMPASS and its function during histone methylation, a key modification that regulates gene expression.
Joseph Bass, MD, PhD, chief of Endocrinology, Metabolism and Molecular Medicine, focuses his research on illuminating how the body’s clocks regulate feeding behavior and glucose metabolism, and identifies how disruptions in that overarching circadian system play a role in metabolic disease.
Northwestern Medicine scientists have identified the unique targets of two enzymes that activate ubiquitination, a key modification of proteins that controls a variety of cellular processes.
A Northwestern Medicine study, led by a PhD student, found that overexpressing a protein called CREB improved memory impairments in aged rats.
Northwestern and Stanford scientists have uncovered new details on the structure of herpesviruses that allow them to initiate a fusion event to infect host cells.
Northwestern Medicine scientists have demonstrated an enhanced approach to targeting a type of inflammatory cell involved in atherosclerosis.