Northwestern Medicine scientists have demonstrated an important role for the methylation of the amino terminus of a specific protein in maintaining centromere function and chromosome segregation, both important in cell division.
Browsing: Scientific Advances
Targeting a molecule called B7-H4 may lead to the development of new therapies that boost the immune system’s ability to fight cancer, according to a review published in the journal Immunological Reviews.
Northwestern Medicine scientists have developed a novel testing platform to assess, in real time, the efficacy of nanomaterials in regulating gene expression.
Northwestern Medicine scientists have mapped the complete structure of a voltage-gated sodium channel, proteins in the membrane of cells that play an important role in many diseases.
Northwestern Medicine scientists have uncovered a novel pathway in the regulation of cellular iron, findings that were published in the Journal of Clinical Investigation.
Northwestern Medicine scientists and collaborators have shown that a protein thought to form calcium ion channels instead regulates the activity of another member of the family to modulate immune responses.
A new study defined the architecture of nuclear lamins, the fibrous proteins in a cell’s nucleus, providing further insights into their role in cell structure.
Revolutionary nanomaterials developed at Northwestern could make it possible to repair tissues and organs spanning from bone and cartilage to muscle and brain tissues.
Northwestern Medicine scientists identified the process by which a calcium channel called the CRAC channel opens and closes, and how mutations in the channel structures that control its opening cause disease.
A paper published in Molecular Cell provides new insight into a protein complex called COMPASS and its function during histone methylation, a key modification that regulates gene expression.