Northwestern Medicine scientists identified the process by which a calcium channel called the CRAC channel opens and closes, and how mutations in the channel structures that control its opening cause disease.
Browsing: Scientific Advances
A paper published in Molecular Cell provides new insight into a protein complex called COMPASS and its function during histone methylation, a key modification that regulates gene expression.
Joseph Bass, MD, PhD, chief of Endocrinology, Metabolism and Molecular Medicine, focuses his research on illuminating how the body’s clocks regulate feeding behavior and glucose metabolism, and identifies how disruptions in that overarching circadian system play a role in metabolic disease.
Northwestern Medicine scientists have identified the unique targets of two enzymes that activate ubiquitination, a key modification of proteins that controls a variety of cellular processes.
A Northwestern Medicine study, led by a PhD student, found that overexpressing a protein called CREB improved memory impairments in aged rats.
Northwestern and Stanford scientists have uncovered new details on the structure of herpesviruses that allow them to initiate a fusion event to infect host cells.
Northwestern Medicine scientists have demonstrated an enhanced approach to targeting a type of inflammatory cell involved in atherosclerosis.
From 3-D printed hyperelastic bones to the nuclear membrane of immature red blood cells, scientific images bring to life the range of research published by Feinberg faculty and students in 2016.
Northwestern Medicine scientists showed how a microRNA family regulates aspects of autophagy and macropinocytosis in the stem cell–enriched limbal epithelium of the eye.
Northwestern Medicine scientists have demonstrated an alternate method of signaling used by proteins called group I metabotropic glutamate receptors, a finding that could be used to develop novel drug treatments for many neurological disorders.