A team of scientists has identified thousands of lincRNAs — long non-coding RNA molecules produced by so-called “junk DNA” — that are unique to human fat cells and may play an important role in fat metabolism.
Browsing: Scientific Advances
Northwestern Medicine scientists have discovered the activation mechanism of a calcium channel, providing new insights for future drug development targeting this calcium signaling pathway.
A team of scientists has identified a key enhancer of Sox9 — a gene critical for male sex development — and demonstrated that deleting the enhancer results in male-to-female sex reversal in animal models.
Enhancing autophagy, the system that recycles old or dysfunctional cells, could have therapeutic effects in a variety of aging-related diseases, according to a pair of Northwestern Medicine studies.
A Northwestern Medicine study has expanded the understanding of nicotine’s influences on the brain’s reward pathway, with implications for the development of anti-addiction therapies.
A study, published in Proceedings of the National Academy of Sciences, provides new insights into the organization of a key protein called cadherin within structures called adherens junctions, which help cells stick together.
New study demonstrates the midbrain’s role in encoding identity errors and how those are used to update expectations in the orbitofrontal cortex.
Scientists found more than 100 possible cancer-causing mutations and defective alleles in a large-scale genetic analysis of pediatric cancers that was co-authored by Elizabeth Perlman, MD, and published in Nature.
The newly-launched Center for Autism and Neurodevelopment is a translational science hub that aims to investigate the neurobiology of autism and facilitate the development of new treatments.
A team of scientists has developed a new technique that allows investigators to better study the effects of nicotine on brain cells.