Browsing: Scientific Advances

Northwestern Medicine investigators have developed a method to measure protein expression in an individual neuron type, according to a study published in Molecular Psychiatry.

The lab of Yongchao C. Ma, PhD, has discovered a fundamental biological mechanism that could lead to new treatments for neurological diseases, such as spinal muscular atrophy (SMA) and autism, as well as different cancers.

Scientists have developed a machine-learning approach to track the evolution of the COVID-19 virus and potentially others, according to a study published in the Proceedings of the National Academy of Sciences.

Investigators led by Issam Ben-Sahra, PhD, have discovered how cellular metabolism fluctuates in response to changes in levels of pyrimidines, metabolites used by cells to make DNA and RNA, according to a recent study published in Science.

Northwestern Medicine scientists have developed a method to identify and characterize microproteins, a development which opens the door for understanding physiology and disease at a molecular level not possible until now, according to findings published in Nature Communications.

Scientists have characterized how non-muscle myosin assembles in cells using the latest advances in technology only available at Northwestern and a handful of institutions worldwide, according to a study published in the Journal of Cell Biology.

As GLP-1 receptor agonist medications like semaglutide have been shown to be effective at helping patients lose weight, scientists are now asking, whether they can treat other conditions where obesity is a risk factor. Most recently, initial studies have shown that they can reduce the risk of cardiovascular disease by reducing overall body weight.

A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.

Scientists have discovered a neuronal pathway involved in how the brain encodes the transition to high-intensity fear response behaviors required for survival, according to a study published in Nature.

A neurotransmitter previously thought to only calm neurons may also play a role in waking them up, according to a study published in the journal PLOS Biology, a discovery which upends conventional theories of how the neurotransmitter works in the brain.