Category: Scientific Advances
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Mitochondria Support Immune Response to Central Nervous System Injuries
Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of immune cells called microglia, but do help them respond to demyelinating injury, according to a study published in Nature Metabolism.
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Understanding the Role of RNA Methylation in Cancer
RNA modifications could serve as a therapeutic target for certain types of cancer, according to a new study published in Molecular Cell which sheds new light on the complex process underlying RNA transcription.
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Protein May Hold Key to Transplant Tolerance
Northwestern Medicine investigators have uncovered how a single protein contributes to heart transplant tolerance in mice, according to a study published in the Proceedings of the National Academy of Sciences.
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Improving Measurement of Gene Expression in Single Cells
Northwestern Medicine scientists have developed a new technique to identify individual cells for RNA sequencing, which will empower scientists to gather more accurate and precise scientific data, according to details published in Cell Genomics.
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Investigating DNA Flexibility for the Creation of New Biomaterials
Northwestern investigators have demonstrated how manipulating DNA chemistry can alter its structure and flexibility and enable the realization of new materials useful in medicine and the life sciences, according to a study published in Science Advances.
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Transplant Research Thrives Through Collaboration
A map of the Northwestern University Transplant Outcomes Research Collaborative (NUTORC) Network looks like an intricate spiderweb. Hovering over one investigator’s name, you see the many investigators they are connected with through publications and research collaboration.
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Genetic Mechanisms May Reveal Retinal Vascular Disease Therapeutic Targets
Northwestern Medicine investigators have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve as therapeutic targets for retinal vascular disease, according to findings published in Nature Communications.
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Improving Models to Study the Human Heart
Northwestern Medicine scientists have developed a new method of measuring and optimizing the maturation process of cultured heart cells, an approach that will set the future standard for a commonly used cell model in scientific research, according to details published in Cell Reports.
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Leading Prostate Cancer Research for More than 20 Years
Prostate cancer is the most common type of cancer in men and is currently the second-leading cause of death in men in the U.S. In 2001, the National Cancer Institute established seven Specialized Programs of Research Excellence (SPORE) in prostate cancer across the U.S., one of which includes the Robert H. Lurie Comprehensive Cancer Center…
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How Herpes Hijacks a Ride into Cells
Northwestern Medicine scientists have discovered how herpes viruses hijack cellular transport processes to infiltrate the nervous system, according to a study published in the Proceedings of the National Academy of Sciences.
