Scientists Discover Novel Mechanism Underlying ALS and Related Dementia
A study has identified a new mechanism for how a gene mutation leads to the death of neurons in amyotrophic lateral sclerosis and a related form of dementia.
Browsing: Disease Discoveries
Brain Rewiring in Parkinson’s Disease May Contribute to Abnormal Movement
A study published in Neuron suggests the brain’s own compensatory mechanisms contribute to the debilitating motor symptoms of Parkinson’s disease.
Genomic Analysis Offers Insights into Cause of Wilms Tumor
A comprehensive genomic analysis of the most common kidney cancer in children – found genetic mutations involving two distinct processes, potentially providing new opportunities for future treatments.
Scientists Discover Key Cellular Mechanism Underlying Parkinson’s Disease
The major features of Parkinson’s disease have been linked to a toxic cascade beginning with oxidized dopamine, providing a possible therapeutic pathway.
Novel Approach Offers New Insights Into HIV’s Lifecycle
Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions to be connected to infectivity.
Scientists Identify Mutations in Venous Valve Disease
Mutations in the genes FOXC2 and GJC2 are associated with defects in venous valves, according to a new study published in the Journal of Experimental Medicine.
Genetic Risk for Lupus Tied to Ancestry
A Northwestern Medicine study analyzing the genomes of more than 27,000 individuals has uncovered that ethnic disparities in lupus diagnoses have a genetic basis.
Novel Screening Method Reveals Glioblastoma Drug Target
Scientists used a new approach to identify a promising therapeutic target for glioblastoma, which was previously overlooked in traditional approaches.
Nanomedicine Opens Door to Precision Medicine for Brain Tumors
Early phase Northwestern Medicine research has demonstrated a potential new therapeutic strategy for treating glioblastoma.
Root of Cardiac Fibrosis Defined
Northwestern Medicine scientists identified a novel molecular mechanism that regulates scar formation in the heart, a symptom of aging and heart disease.